In the age of knowledge economy, the knowledge of the enterprise creates most of the competitive advantages. The produce of one enterprise not only relies on hardware resources but also its knowledge. The medical industry is a capital, human resource, and knowledge concentrated health business. Therefore, the managers of medical industry are paying more attention on knowledge management. Due to the technology, a lot of the things that could not be done before are now able to do. Knowledge management is one of the things. When implementing knowledge management company used to face a lot of difficulties. First, knowledge only exists and storage in employees’ mind therefore can not be note down systematically. Second, if it is able to be note down and document, the process of finding and reading the document is complicated. Hence, it became the obstacle of spreading knowledge. In the old days, although managers noticed the importance of knowledge management, but without the technology and the right tools its merely impossible to implement. Nowadays, knowledge management is becoming the future trend of management because of the technology. Especially in the age of knowledge economy, knowledge management become critical to the success of hospitals. The purpose of the thesis is to find out how should Miou-Li General Hospital make application of knowledge management and the ways of turning experience into knowledge. Seeing knowledge as a valuable property and apply knowledge management to enhance the value, in order to ensure the competitiveness of Miou-Li General Hospital. As situated in the knowledge based economy, how to effectively gather, sort, spread, and use knowledge become critical to the success of Miou-Li General Hospital. If it can successfully apply knowledge management in the hospital, not only can ensure the quality of the hospital but also the competitiveness in the medical industry.