Most studies of behavioral science use a nomotheic approach where a norm is established based on the performance of a group of people. Appropriate statistical analyses are then applied to the group measurements. Although the nomothetic approach has its value, ipsative approach or individual relationship approach is also necessary. Stephenson first proposed Q-methodology in 1953. This methodology emphasizes people's subjective feeling. The Q-sort procedure is used to collect data for statistical analysis in order to understand individual behavioral changes or clustering in a group. Q-methodology is a relatively new and powerful methodological technique. However, due to lack of systemic review and dissemination, Q-methodology has not been used by researchers frequently and has received little attention in Taiwan. This article focuses on the history, meanings, indications, technical procedures, data analysis, advantages, and limitations of Q- methodology. Hopefully, Q-methodology will be used widely in the future by nurse researchers to understand people's subjective feeling.