In this paper, the author expresses his own idea about the cultural dissemination and transformation between China and the West through the review of Zhang Xiping’s new book, the History of Philosophical and Religious Exchange in Early Period between China and Europe. In author’s view, the greatest feature of the book is to describe the cultural exchanges and dissemination in the later Ming and early Qing Dynasty, supplying a whole scene of it to point out the equal character which it has., thus to correct the previous relevant ideas in this research area. The author says, according to the general law of cultural dissemination interpreted by the study of culture, the culture in strong and high position must expand and replace those cultures in weak and low positions. The acceptance of the idea made many scholars to believe that any cultural dissemination has been led to the cultural confrontation, there is never any equal cultural exchange and real fusion. Therefore, if we fond there was an equal cultural dissemination in the history, the water runs to the lower place will not be a definite law in the cultural exchange, neither the strong culture replaces the weak culture. It is also the author’s idea that in a cu1tural system religion and philosophy is located in the kernel of the spiritual layer. Whether there is or not the exchange of religion and philosophy among cultures, which is a measure to judge the degree of cultural exchange and dissemination. For the effectiveness of the exchange, the side of the spread will adjust its form and content of religion and philosophy, while the side of the receive also adopt the foreign thought through the interpretation, the translation and recreation. This kind of mutual interpretation and recreation supplies an occasion for spiritual fusion. Under the current globalization, the Chinese scholars should promote the equal exchange and dialogue with a peaceful metal attitude and high ideal to climb the cu1tural peak of the world.