Trade secret is some kind of the most important assets in enterprises. Once the valuable information conforms to legal requirements, then they become the protected objective matters, named trade secret, under law. Trade secret is are not automatically possessed the legal position, but constructed by the reasonable effort to protect under managerial practice, and also depended on the opinion of justice system. United States is the earliest country to legislate law to protect valuable information other then patent, trade mark and copyright, as an additional pattern of intellectual property right. According to the common law system, US practice of management of trade secret is seriously subjected by the judiciary opinion of their courts, specially the opinion from those United States Court of Appeal’s. The purpose of this research is to point out some issues that influence the operation of trade secrets protection under managerial respects from selected cases.