本研究以自我調整模式之理論為背景，採橫斷式、探討性和相關性研究設計，旨在探討肌無力症病患的疾病感受、情緒與生活品質之相關性。研究對象為台北市某醫院之肌無力症門診病患，採方便取樣，共選取100名病患進行問卷調查。問卷內容包括：人口學特質與疾病相關資料、疾病感受問卷調查表、醫院焦慮與憂鬱量表，以及生活品質量表等五部分。研究結果顯示疾病症狀辨識與焦慮、憂鬱、生理層面和心理層面生活品質呈顯著相關；疾病原因與焦慮、生理層面和心理層面生活品質呈顯著相關；疾病時間與焦慮和生理層面生活品質呈顯著相關；疾病影響與焦慮、憂鬱、生理層面、心理層面生活品質呈顯著相關；焦慮與憂鬱呈正相關；憂鬱與生理層面、心理層面生活品質呈負相關。逐步迴歸分析結果顯示疾病期間、憂鬱和疾病影響，可有意義的解釋24.2%生理層面生理品質的變異量；焦慮、憂鬱和疾病影響共可以解釋54.1%心理層面生活品質的變異量。研究結果期能提供臨床護理人員設計護理措施之參考。

　　　　　The purpose of this study is to test relationships among illness perceptions, mood and quality of life in patients with myasthenia gravis (MG). The conceptual model for the study is derived from Leventhal's self-regulation model. The study used a cross sectional, correlational design. One hundred patients participated in this study. Measures include Illness Perception Questionnaire, the Hospital Anxiety and Depression Scale, and Medical Outcome Study Short-Form General Health Survey MOS SF-36. Correlational results indicated that illness identity was related to anxiety, depression, and physical and mental components of quality of life (QOL). Illness cause was related to anxiety, and physical and mental components of QOL. Illness timeline was related to anxiety and physical components of QOL. Illness consequence was related to anxiety, depression, and physical and mental components of QOL. 24.2% of the variance in physical components of QOL can be explained by timeline, depression and consequence; a total of 54.1% of the variance in mental components of QOL can be explained by anxiety, depression, consequence and disability. These findings could provide vital information for nurses taking care of MG patients.