Vaclav Havel, president of the Czech Republic, recently stated that “the crisis of the much-needed global responsibility is in principle due to the fact that we have lost the certainty that the Universe…has a definite meaning and follows a definite purpose.” I would hasten to agree that if we fail to trust that the cosmos is, at heart, the unfolding of a transcending purpose, our ethical aspirations and our zest for life will eventually wither on the vine. Today, I believe we need to recapture in a fresh way the religious sense of a purposeful universe. The future of religion is, in a very deep sense, tied to the plausibility of the idea that the universe is here for a reason. The question, however, is whether we can we embrace such a sweeping idea without contradicting the discoveries of science. Yet, I shall argue here, with the help of such scientifically enlightened religious thinkers as Michael Polanyi, Teilhard de Chardin and Alfred North Whitechead, that we may plausibly view the discoveries of natural science as a springboard toward a wider and more vibrant sense of an ultimately meaningful universe than has ever been available to us before.