目的：本研究為嚴重急性呼吸道症候群(SARS)防治工作對院內感染的影響。 方法：收集2002年至2004年5-7月北部某醫學中心住院病人院內感染資料，病人數分別為14,298人(2002年)、9,922人(2003年)及16,362人(2004年)，感染人次數分別為366人(2002年)、328人(2003年)及476人(2004年)，並分析其差異。 結果：SARS以前之院內感染率為2.56%，過後則為2.91%，與SARS流行期間3.31%比較均達統計之顯著意義(p<0.01)，隔離病患的感染率則在SARS流行期間比非SARS期間均低，感染部位均為泌尿道感染最高。非SARS流行期間以S. aureus菌株數佔率最多，流行期間為P. aeruginosa。 結論：SARS期間的防治措施對院內感染的控制有正面助益。 建議：確遵勤洗手、無菌通及消毒、與隔離措施的實施。

To understand the impact of SARS control on nosocomial infection, we compared the incidence of nosocomial infection in a medical center from May to July in 2003 (SARS period) to that in the previous and the following year. There were 366 and 328 and 476 nosocomial infection patients in 14298 and 9922 and 16362 admission patients in 2002 to 2003 respectively during that period. The infection rate before and after SARS outbreak was 2.56% and 2.91%. The infection rate during SARS outbreak was 3.31%. The difference between he rate before and after SARS outbreak respectively with the rate during SARS outbreak were significant (p<0.01); urinary tract infection was the most common infection. S. aureus was the most common agent before and after SARS outbreak and the P. aeruginosa was the most common agent during SARS outbreak. The management during SARS break was very meaningful. The prevention principle such as washing hands should be encouraged to avoid nosocomial infection.