The purpose of this study was to understand the Clinical Practicum Instruction Satisfaction at an Institute of Health Science and Technology of the nursing preceptor. The data was to collected by questionnaires. One hundreds and twelve nursing preceptors Participated in this study. The results was analyzed by 「SPSS 10.0」 Computer soft-wave. The results were as followings: Nursing Preceptor: More feel “satisfactory” over clinical practicum instruction satisfaction . More feel “satisfactory” over unit superiors’ support. The higher unit superiors’ support, the higher teaching satisfaction . Factors of influence: those who have no children. The results of multiple regression show stat “unit superiors’ support”. “work unit” was the clinical practicum instruction satisfaction predictors. The results of this study would provide Nursing