:::

詳目顯示

回上一頁
題名:Pathogenesis of Neurodegenerative Diseases and the Effect of Natural Products on Nitric Oxide Production Implicating in These Diseases
書刊名:中醫藥雜誌
作者:沈郁強蕭永基宋晏仁王春女
作者(外文):Shen, Yuh-chiangShiao, Young-jiSung, Yen-jenWang, Chuen-neu
出版日期:2005
卷期:16:2/3
頁次:頁63-87
主題關鍵詞:一氧化氮急性神經退化神經毒性氧化壓力發炎粒線體功能異常天然物Nitric oxideAcute neurodegenerationNeurotoxicityOxidative stressInflammationMitochondrial dysfunctionNatural products
原始連結:連回原系統網址new window
相關次數:
  • 被引用次數被引用次數:期刊(0) 博士論文(0) 專書(0) 專書論文(0)
  • 排除自我引用排除自我引用:0
  • 共同引用共同引用:0
  • 點閱點閱:1
期刊論文
1.Surh, Y. J.、Chun, K. S.、Cha, H. H.、Han, S. S.、Keum, Y. S.、Park, K. K.、Lee, S. S.(2001)。Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: down-regulation of COX-2 and iNOS through suppression of NF-kappa B activation。Mutat. Res.,480/481,243-268。  new window
2.Daurer, W.、Przedborski, S.(2003)。Parkinson's disease: Mechanisms and models。Neuron,39(6),889-909。  new window
3.Wiesinger, H.(2001)。Arginine metabolism and the synthesis of nitric oxide in the nervous system。Prog Neurobiol,64,365-391。  new window
4.Koesling, D.、Russwurm, M.、Mergia, E.、Mullershausen, F.、Friebe, A.(2004)。Nitric oxide-sensitive guanylyl cyclase: structure and regulation。Neurochem Int,45,813-819。  new window
5.Boehning, D.、Snyder, S. H.(2003)。Novel neural modulators。Annu Rev Neurosci,26,105-131。  new window
6.Bredt, D. S.、Snyder, S. H.(1990)。Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme。Proc Natl Acad Sci USA,87,682-685。  new window
7.Bredt, D. S.、Ferris, C. D.、Snyder, S. H.(1992)。Nitric oxide synthase regulatory sites. Phosphorylation by cyclic AMP-dependent protein kinase, protein kinase C, and calcium/calmodulin protein kinase; identification of flavin and calmodulin binding sites。J. Biol. Chem.,267,10976-10981。  new window
8.Brenman, J. E.、Chao, D. S.、Gee, S. H.、McGee, A. W.、Craven, S. E.、Santillano, D. R.、Wu, Z.、Huang, F.、Xia, H.、Peters, M. F.、Froehner, S. C.、Bredt, D. S.(1996)。Interaction of nitric oxide synthase with the postsynaptic density protein PSD-95 and alphal-syntrophin mediated by PDZ domains。Cell,84,757-767。  new window
9.Yamada, M.、Huang, Z.、Dalkara, T.、Endres, M.、Laufs, U.、Waeber, C.、Huang, P. L.、Liao, J. K.、Moskowitz, M. A.(2000)。Endothelial nitric oxide synthase-dependent cerebral blood flow augmentation by L-arginine after chronic statin treatment。J Cereb Blood Flow Metab,20,709-717。  new window
10.Marks-Konczalik, J.、Chu, S. C.、Moss, J.(1998)。Cytokine-mediated transcriptional induction of the human inducible nitric oxide synthase gene requires both activator protein 1 and nuclear factor kappaB-binding sites。J Biol Chem,273,22201-22208。  new window
11.Israel, A.(2000)。The IKK complex: an integrator of all signals that activate NF-kappaB?。Trends Cell Biol,10,129-133。  new window
12.Karin, M.、Delhase, M.(2000)。The I kappa B kinase (IKK) and NF-kappa B. key elements of proinflammatory signaling。Semin Immunol,12,85-98。  new window
13.Dell'Albani, P.、Santangelo, R.、Torrisi, L.、Nicoletti, V. G.、de Vellis, J.、Giuffrida Stella, A. M.(2001)。JAK/STAT signaling pathway mediates cytokine-induced iNOS expression in primary astroglial cell cultures。Journal of Neuroscience Research,65,417-424。  new window
14.Baeuerle, P. A.、Henkel, T.(1994)。Function and activation of NF-kappa B in the immune system。Annu Rev Immunol,12,141-179。  new window
15.Thanos, D.、Maniatis, T.(1995)。NF-kappa B. a lesson in family values。Cell,80,529-532。  new window
16.Gao, J.、Morrison, D. C.、Parmely, T. J.、Russell, S. W.、Murphy, W. J.(1997)。An interferon-gamma-activated site (GAS) is necessary for full expression of the mouse iNOS gene in response to interferon-gamma and lipopolysaccharide。J Biol Chem,272,1226-1230。  new window
17.Kovarik, P.、Stoiber, D.、Novy, M.、Decker, T.(1998)。Statl combines signals derived from IFN-gamma and LPS receptors during macrophage activation。Embo J,17,3660-3668。  new window
18.Ohmori, Y.、Hamilton, T. A.(2001)。Requirement for STAT1 in LPS-induced gene expression in macrophages。J Leukoc Biol,69,598-604。  new window
19.Ramana, C. V.、Gil, M. P.、Schreiber, R. D.、Stark, G. R.(2002)。Statl-dependent and -independent pathways in IFN-gammadependent signaling。Trends Imniunol,23,96-101。  new window
20.Schroder, K.、Hertzog, P. J.、Ravasi, T.、Hume, D. A.(2004)。Interferon-gamma: an overview of signals, mechanisms and functions。J Leukoc Biol,75,163-189。  new window
21.Pahan, K.、Jana, M.、Liu, X.、Taylor, B. S.、Wood, C.、Fischer, S. M.(2002)。Gemfibrozil, a lipid-lowering drug, inhibits the induction of nitric-oxide synthase in human astrocytes。J Biol Chem,277,45984-45991。  new window
22.Eferl, R.、Wagner, E. F.(2003)。AP-1. a double-edged sword in tumorigenesis。Nat Rev Cancer,3,859-868。  new window
23.Díaz-Guerra, M. J.、Bodelon, O. G.、Velasco, M.、Whelan, R.、Parker, P. J.、Bosca, L.(1996)。Up-regulation of protein kinase Cepsilon promotes the expression of cytokine-inducible nitric oxide synthase in RAW 264.7 cells。J Biol Chem,271,32028-32033。  new window
24.Bhat, N. R.、Zhang, P.、Lee, J. C.、Hogan, E. L.(1998)。Extra cellular signal-regulated kinase and p38 subgroups of mitogenactivated protein kinases regulate inducible nitric oxide synthase and tumor necrosis factor-alpha gene expression in endotoxin-stimulated primary glial cultures。J Neurosci,18,1633-1641。  new window
25.Chen, C. C.、Wang, J. K.、Chen, W. C.、Lin, S. B.(1998)。Protein kinase C eta mediates lipopolysaccharide-induced nitric-oxide synthase expression in primary astrocytes。J Biol Chem,273,19424-19430。  new window
26.Carpenter, L.、Cordery, D.、Biden, T. J.(2001)。Protein kinase Cdelta activation by interleukin-1 beta stabilizes inducible nitric-oxide synthase mRNA in pancreatic beta-cells。J Biol Chem,276,5368-5374。  new window
27.Syntichaki, P.、Tavemarakis, N.(2003)。The biochemistry of neuronal necrosis: rogue biology?。Nat Rev Neurosci,4,672-684。  new window
28.Lo, E. H.、Dalkara, T.、Moskowitz, M. A.(2003)。Mechanisms, challenges and opportunities in stroke。Nat Rev Neurosci,4,399-415。  new window
29.Allan, S. M.、Rothwell, N. J.(2001)。Cytokines and acute neurodegeneration。Nat Rev Neurosci,2,734-744。  new window
30.Lipton, P.(1999)。Ischemic cell death in brain neurons。Physiol Rev,79,1431-1568。  new window
31.Lee, J. M.、Zipfel, G. J.、Choi, D. W.(1999)。The changing landscape of ischemic brain injury mechanisms。Nature,399,A7-A14。  new window
32.Peng, W.、Hucks, D.、Priest, R. M.、Kan, Y. M.、Ward, J. P.(1996)。Ligustrazine-induced endothelium-dependent relaxation in pulmonary arteries via an NO-mediated and exogenous L-arginine-dependent mechanism。Br J Pharmacol,119,1063-1071。  new window
33.Beckman, J. S.(1996)。Oxidative damage and tyrosine nitration from peroxynitrite。Chem Res Toxicol,9,836-844。  new window
34.Frijns, C. J.、Kappelle, L. J.(2002)。Inflammatory cell adhesion molecules in ischemic cerebrovascular disease。Stroke,33,2115-2122。  new window
35.Madrigal, J. L.、Moro, M. A.、Lizasoain, I.、Lorenzo, P.、Leza, J. C.(2002)。Stress-induced increase in extra cellular sucrose space in rats is mediated by nitric oxide。Brain Res,938,87-91。  new window
36.Nicotera, P.、Leist, M.、Fava, E.、Berliocchi, L.、Volbracht, C.(2000)。Energy requirement for caspase activation and neuronal cell death。Brain Pathol,10,276-282。  new window
37.Yu, S. P.、Choi, D. W.(2000)。Ions, cell volume, and apoptosis。Proc Natl Acad Sci U S A,97,9360-9362。  new window
38.Namura, S.、Zhu, J.、Fink, K.、Endres, M.、Srinivasan, A.、Tomaselli, K. J.、Yuan, J.、Moskowitz, M. A.(1998)。Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia。J Neurosci,18,3659-3668。  new window
39.Wei, M. C.、Zong, W. X.、Cheng, E. H.、Lindsten, T.、Panoutsakopoulou, V.、Ross, A. J.、Roth, K. A.、MacGregor, G. R.、Thompson, C. B.、Korsmeyer, S. J.(2001)。Proapoptotic BAX and BAK. a requisite gateway to mitochondrial dysfunction and death。Science,292,727-730。  new window
40.Qiu, J.、Whalen, M. J.、Lowenstein, P.、Fiskum, G.、Fahy, B.、Darwish, R.、Aarabi, B.、Yuan, J.、Moskowitz, M. A.(2002)。Upregulation of the Fas receptor death-inducing signaling complex after traumatic brain injury in mice and humans。J Neurosci,22,3504-3511。  new window
41.Susin, S. A.、Lorenzo, H. K.、Zamzami, N.、Marzo, I.、Snow, B. E.、Brothers, G. M.、Mangion, J.、Jacotot, E.、Costantini, P.、Loeffler, M.、Larochette, N.、Goodlett, D. R.、Aebersold, R.、Siderovski, D. P.、Penninger, J. M.、Kroemer, G.(1999)。Molecular characterization of mitochondrial apoptosis-inducing factor。Nature,397,441-446。  new window
42.Madrigal, J. L.、Caso, J.、Hurtado, O.、Lizasoain, I.、Moro, M. A.、Lorenzo, P.、Leza, J. C.(2004)。Brain oxidative markers in stress: possible new drug targets against neuroinflammation。Curr Neuropharmacol,2,183-189。  new window
43.Appleby, S. B.、Ristimaki, A.、Neilson, K.、Narko, K.、Hla, T.(1994)。Structure of the human cyclo-oxygenase-2 gene。Biochem J,302,723-727。  new window
44.Maurice, T.、Lockhart, B. P.、Privat, A.(1996)。Amnesia induced in mice by centrally administered beta-amyloid peptides involves cholinergic dysfunction。Brain Res,706,181-193。  new window
45.Yankner, B. A.(1996)。Mechanisms of neuronal degeneration in Alzheimer's disease 2。Neuron,16,921-932。  new window
46.MacManus, A.、Ramsden, M.、Murray, M.、Henderson, Z.、Pearson, H. A.、Campbell, V. A.(2000)。Enhancement of (45)Ca(2+) influx and voltage-dependent Ca(2+) channel activity by beta-amyloid-(1-40) in rat cortical synaptosomes and cultured cortical neurons. Modulation by the proinflammatory cytokine interleukin-lbeta。J Biol Chem,275,4713-4718。  new window
47.Pike, C. J.、Ramezan-Arab, N.、Cotman, C. W.(1997)。Beta-amyloid neurotoxicity in vitro: evidence of oxidative stress but not protection by antioxidants。J Neurochem,69,1601-1611。  new window
48.Behl, C.、Davis, J. B.、Lesley, R.、Schubert, D.(1994)。Hydrogen peroxide mediates amyloid beta protein toxicity。Cell,77,817-827。  new window
49.Wang, C. N.、Chi, C. W.、Lin, Y. L.、Chen, C. F.、Shiao, Y. J.(2001)。The neuroprotective effects of phytoestrogens on amyloid beta protein-induced toxicity are mediated by abrogating the activation of caspase cascade in rat cortical neurons。J Biol Chem,276,5287-5295。  new window
50.Torreilles, F.、Salman-Tabcheh, S.、Guerin, M.、Torreilles, J.(1999)。Neurodegenerative disorders: the role of peroxynitrite。Brain Res Brain Res Rev,30,153-163。  new window
51.Lorton, D.、Kocsis, J. M.、King, L.、Madden, K.、Brunden, K. R.(1996)。Beta-Amyloid induces increased release of interleukin-1 beta from lipopolysaccharide-activated human monocytes。J Neuroimmunol,67,21-29。  new window
52.Dickson, D. W.、Lee, S. C.、Mattiace, L. A.、Yen, S. H.、Brosnan, C.(1993)。Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease。Glia,7,75-83。  new window
53.Tan, J.、Town, T.、Mullan, M.(2002)。CD40-CD40L interaction in Alzheimer's disease。Curr Opin Pharmacol,2,445-451。  new window
54.Bonaiuto, C.、McDonald, P. P.、Rossi, F.、Cassatella, M. A.(1997)。Activation of nuclear factor-kappa B by beta-amyloid peptides and interferon-gamma in murine microglia。J Neuroimmunol,77,51-56。  new window
55.Heese, K.、Hock, C.、Otten, U.(1998)。Inflammatory signals induce neurotrophin expression in human microglial cells。J Neurochem,70,699-707。  new window
56.Meda, L.、Cassatella, M. A.、Szendrei, G. I.、Otvos, L.、Baron, P.、Villalba, M.、Ferrari, D.、Rossi, F.(1995)。Activation of microglial cells by beta-amyloid protein and interferon-gamma。Nature,374,647-650。  new window
57.McMillian, M.、Kong, L. Y.、Sawin, S. M.、Wilson, B.、Das, K.、Hudson, P.、Hong, J. S.、Bing, G.(1995)。Selective killing of cholinergic neurons by microglial activation in basal forebrain mixed neuronal/glial cultures。Biochem Biophys Res Commun,215,572-577。  new window
58.Hartmann, H.、Eckert, A.、Muller, W. E.(1993)。Beta-Amyloid protein amplifies calcium signaling in central neurons from the adult mouse。Biochem Biophys Res Commun,194,1216-1220。  new window
59.Varadarajan, S.、Yatin, S.、Aksenova, M.、Butterfield, D. A.(2000)。Review: Alzheimer's amyloid beta-peptide-associated free radical oxidative stress and neurotoxicity。J Struct Biol,130,184-208。  new window
60.Noda, M.、Nakanishi, H.、Akaike, N.(1999)。Glutamate release from microglia via glutamate transporter is enhanced by amyloid-beta peptide。Neuroscience,92,1465-1474。  new window
61.Yang, S. N.、Hsieh, W. Y.、Liu, D. D.、Tsai, L. M.、Tung, C. S.、Wu, J. N.(1998)。The involvement of nitric oxide in synergistic neuronal damage induced by beta-amyloid peptide and glutamate in primary rat cortical neurons。Chin J Physiol,41,175-179。  new window
62.Brown, G. C.(1999)。Nitric oxide and mitochondrial respiration。Biochim Biophys Acta,1411,351-369。  new window
63.Vaucher, E.、Linville, D.、Hamel, E.(1997)。Cholinergic basal forebrain projections to nitric oxide synthase-containing neurons in the rat cerebral cortex。Neuroscience,79,827-836。  new window
64.Beckman, J. S.、Koppenol, W. H.(1996)。Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly。Am J Physiol,271,1424-1437。  new window
65.Hensley, K.、Maidt, M. L.、Yu, Z.、Sang, H.、Markesbery, W. R.、Floyd, R. A.(1998)。Electrochemical analysis of protein nitrotyrosine and dityrosine in the Alzheimer brain indicates region-specific accumulation。J Neurosci,18,8126-8132。  new window
66.Bossy-Wetzel, E.、Schwarzenbacher, R.、Lipton, S. A.(2004)。Molecular pathways to neurodegeneration。Nat Med,10(Suppl),S2-S9。  new window
67.Vila, M.、Przedborski, S.(2004)。Genetic clues to the pathogenesis of Parkinson's disease。Nat Med,10(Suppl),S58-S62。  new window
68.Conway, K. A.、Lee, S. J.、Rochet, J. C.、Ding, T. T.、Williamson, R. E.、Lansbury, P. T.(2000)。Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy。Proc Natl Acad Sci USA,97,571-576。  new window
69.Voiles, M. J.、Lee, S. J.、Rochet, J. C.、Shtilerman, M. D.、Ding, T. T.、Kessler, J. C.、Lansbury, P. T.(2001)。Vesicle permeabilization by protofibrillar alpha-synuclein: implications for the pathogenesis and treatment of Parkinson's disease。Biochemistry,40,7812-7819。  new window
70.Conway, K. A.、Rochet, J. C.、Bieganski, R. M.、Lansbury, P. T.(2001)。Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct。Science,294,1346-1349。  new window
71.Chung, K. K.、Thomas, B.、Li, X.、Pletnikova, O.、Troncoso, J. C.、Marsh, L.、Dawson, V. L.、Dawson, T. M.(2004)。S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function。Science,304,1328-1331。  new window
72.Yao, D.、Gu, Z.、Nakamura, T.、Shi, Z. Q.、Ma, Y.、Gaston, B.、Palmer, L. A.、Rockenstein, E. M.、Zhang, Z.、Masliah, E.、Uehara, T.、Lipton, S. A.(2004)。Nitrosative stress linked to sporadic Parkinson's disease: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activity。Proc Natl Acad Sci USA,101,10810-10814。  new window
73.Abou-Sleiman, P. M.、Healy, D. G.、Quinn, N.、Lees, A. J.、Wood, N. W.(2003)。The role of pathogenic DJ-1 mutations in Parkinson's disease。Ann Neurol,54,283-286。  new window
74.Taira, T.、Saito, Y.、Niki, T.、Iguchi-Ariga, S. M.、Takahashi, K.、Ariga, H.(2004)。DJ-1 has a role in antioxidative stress to prevent cell death。EMBO Rep,5,213-218。  new window
75.Andersen, J. K.(2004)。Oxidative stress in neurodegeneration: cause or consequence?。Nat Med,10(Suppl),S18-S25。  new window
76.Graham, D. G.(1978)。Oxidative pathways for catecholamines in the genesis of neuromelanin and cytotoxic quinones。Mol Pharmacol,14,633-643。  new window
77.Alam, Z. I.、Jenner, A.、Daniel, S. E.、Lees, A. J.、Caims, N.、Marsden, C. D.、Jenner, P.、Halliwell, B.(1997)。Oxidative DNA damage in the parkinsonian brain: an apparent selective increase in 8 -hydroxyguanine levels in substantia nigra。J Neurochem,69,1196-1203。  new window
78.Jenner, P.(1998)。Oxidative mechanisms in nigral cell death in Parkinson's disease。Mov Disord,13(Suppl 1),24-34。  new window
79.Betarbet, R.、Sherer, T. B.、MacKenzie, G.、Garcia-Osuna, M.、Panov, A. V.、Greenamyre, J. T.(2000)。Chronic systemic pesticide exposure reproduces features of Parkinson's disease。Nat Neurosci,3,1301-1306。  new window
80.Stewart, V. C.、Heales, S. J.(2003)。Nitric oxide-induced mitochondrial dysfunction: implications for neurodegeneration。Free Radic Biol Med,34,287-303。  new window
81.Poderoso, J. J.、Lisdero, C.、Schopfer, F.、Riobo, N.、Carreras, M. C.、Cadenas, E.、Boveris, A.(1999)。The regulation of mitochondrial oxygen uptake by redox reactions involving nitric oxide and ubiquinol。J Biol Chem,274,37709-37716。  new window
82.Furfine, E. S.、Harmon, M. F.、Paith, J. E.、Garvey, E. P.(1993)。Selective inhibition of constitutive nitric oxide synthase by LNG-nitroarginine。Biochemistry,32,8512-8517。  new window
83.Hobbs, A. J.、Higgs, A.、Moncada, S.(1999)。Inhibition of nitric oxide synthase as a potential therapeutic target。Annu Rev Pharmacol Toxicol,39,191-220。  new window
84.Pfeiffer, S.、Leopold, E.、Schmidt, K.、Brunner, F.、Mayer, B.(1996)。Inhibition of nitric oxide synthesis by NG-nitro-Larginine methyl ester (L-NAME): requirement for bioactivation to the free acid, NG-nitro-L-arginine。Br J Pharmacol,118,1433-1440。  new window
85.Furfine, E. S.、Harmon, M. F.、Paith, J. E.、Knowles, R. G.、Salter, M.、Kiff, R. J.、Duffy, C.、Hazelwood, R.、Oplinger, J. A.、Garvey, E. P.(1994)。Potent and selective inhibition of human nitric oxide synthases. Selective inhibition of neuronal nitric oxide synthase by S-methyl-L-thiocitrulline and S-ethyl-L-thiocitrulline。J Biol Chem,269,26677-26683。  new window
86.Salemo, J. C.、Frey, C.、McMillan, K.、Williams, R. F.、Masters, B. S.、Griffith, O. W.(1995)。Characterization by electron paramagnetic resonance of the interactions of L-arginine and L-thiocitrulline with the heme cofactor region of nitric oxide synthase。J Biol Chem,270,27423-27428。  new window
87.Bryk, R.、Wolff, D. J.(1998)。Mechanism of inducible nitric oxide synthase inactivation by aminoguanidine and L-N6-(1-iminoethyl)lysine。Biochemistry,37,4844-4852。  new window
88.Naka, M.、Nanbu, T.、Kobayashi, K.、Kamanaka, Y.、Komeno, M.、Yanase, R.、Fukutomi, T.、Fujimura, S.、Seo, H. G.、Fujiwara, N.、Ohuchida, S.、Suzuki, K.、Kondo, K.、Taniguchi, N.(2000)。A potent inhibitor of inducible nitric oxide synthase, ONO-1714, a cyclic amidine derivative。Biochem Biophys Res Commun,270,663-667。  new window
89.Bryk, R.、Wolff, D. J.(1999)。Pharmacological modulation of nitric oxide synthesis by mechanism-based inactivators and related inhibitors。Pharmacol Ther,84,157-178。  new window
90.Stuehr, D. J.(1999)。Mammalian nitric oxide synthases。Biochim Biophys Acta,1411,217-230。  new window
91.Baek, K. J.、Thiel, B. A.、Lucas, S.、Stuehr, D. J.(1993)。Macrophage nitric oxide synthase subunits. Purification, characterization, and role of prosthetic groups and substrate in regulating their association into a dimeric enzyme。J Biol Chem,268,21120-21129。  new window
92.Xie, Q. W.、Leung, M.、Fuortes, M.、Sassa, S.、Nathan, C.(1996)。Complementation analysis of mutants of nitric oxide synthase reveals that the active site requires two hemes。Proc Natl Acad Sci USA,93,4891-4896。  new window
93.McMillan, K.、Adler, M.、Auld, D. S.、Baldwin, J. J.、Blasko, E.、Browne, L. J.、Chelsky, D.、Davey, D.、Dolle, R. E.、Eagen, K. A.、Erickson, S.、Feldman, R. I.、Glaser, C. B.、Mallari, C.、Morrissey, M. M.、Ohlmeyer, M. H.、Pan, G.、Parkinson, J. F.、Phillips, G. B.、Polokoff, M. A.、Sigal, N. H.、Vergona, R.、Whitlow, M.、Young, T. A.、Devlin, J. J.(2000)。Allosteric inhibitors of inducible nitric oxide synthase dimerization discovered via combinatorial chemistry。Proc Natl Acad Sci USA,97,1506-1511。  new window
94.Ohtsuka, M.、Konno, F.、Honda, H.、Oikawa, T.、Ishikawa, M.、Iwase, N.、Isomae, K.、Ishii, F.、Hemmi, H.、Sato, S.(2002)。PPA250 [3-(2,4-difluorophenyl)-6-[2-[4-(1H-imidazol-1-ylmethyl) phenoxy]ethoxy]-2-phenylpyridine], a novel orally effective inhibitor of the dimerization of inducible nitric-oxide synthase, exhibits an anti-inflammatory effect in animal models of chronic arthritis。J Pharmacol Exp Ther,303,52-57。  new window
95.Wang, T.、Liu, B.、Zhang, W.、Wilson, B.、Hong, J. S.(2004)。Andrographolide reduces inflammation-mediated dopaminergic neurodegeneration in mesencephalic neuron-glia cultures by inhibiting microglial activation。J Pharmacol Exp Ther,308,975-983。  new window
96.Nguyen, M. T.、Awale, S.、Tezuka, Y.、Chien-Hsiung, C.、Radota, S.(2004)。Staminane- and isopimarane-type diterpenes from Orthosiphon stamineus of Taiwan and their nitric oxide inhibitory activity。J Nat Prod,67,654-658。  new window
97.de las Heras, B.、Navarro, A.、Díaz-Guerra, M. J.、Bermejo, P.、Castrillo, A.、Bosca, L.、Villar, A.(1999)。Inhibition of NOS-2 expression in macrophages through the inactivation of NF-kappaB by andalusol。Br J Pharmacol,128,605-612。  new window
98.Li, L.、Shen, Y. M.、Yang, X. S.、Wu, W. L.、Wang, B. G.、Chen, Z. H.、Hao, X. J.(2002)。Effects of spiramine T on antioxidant enzymatic activities and nitric oxide production in cerebral ischemia-reperfusion gerbils。Brain Res,944,205-209。  new window
99.Soliman, K. F.、Mazzio, E. A.(1998)。In vitro attenuation of nitric oxide production in C6 astrocyte cell culture by various dietary compounds。Proc Soc Exp Biol Med,218(4),390-397。  new window
100.Chen, C. J.、Raung, S. L.、Liao, S. L.、Chen, S. Y.(2004)。Inhibition of inducible nitric oxide synthase expression by baicalein in endotoxin/cytokine-stimulated microglia。Biochem Pharmacol,67,957-965。  new window
101.Aldieri, E.、Atragene, D.、Bergandi, L.、Riganti, C.、Costamagna, C.、Bosia, A.、Ghigo, D.(2003)。Artemisinin inhibits inducible nitric oxide synthase and nuclear factor NF-kB activation。FEBS Lett,552,141-144。  new window
102.Wang, C. N.、Shiao, Y. J.、Lin, Y. L.、Chen, C. F.(1999)。Nepalolide A inhibits the expression of inducible nitric oxide synthase by modulating the degradation of IkappaB-alpha and IkappaB-beta in C6 glioma cells and rat primary astrocytes。Br J Pharmacol,128,345-356。  new window
103.Abad, M. J.、Bermejo, P.、Alvarez, M.、Guerra, J. A.、Silvan, A. M.、Villar, A. M.(2004)。Flavonoids and a sesquiterpene lactone from Tanacetum microphyllum inhibit anti-inflammatory mediators in LPS-stimulated mouse peritoneal macrophages。Planta Med,70,34-38。  new window
104.Wang, C. N.、Shiao, Y. J.、Kuo, Y. H.、Chen, C. C.、Lin, Y. L.(2000)。Inducible nitric oxide synthase inhibitors from Saposhnikovia divaricata and Panax quinquefolium。Planta Med,66,644-647。  new window
105.Shiao, Y. J.、Lin, Y. L.、Sun, Y. H.、Chi, C. W.、Chen, C. F.、Wang, C. N.(2005)。Falcarindiol impairs the expression of inducible nitric oxide synthase by abrogating the activation of IKK and JAK in rat primary astrocytes。Br J Pharmacol,144,42-51。  new window
106.Choi, S. S.、Lee, J. K.、Han, E. J.、Han, K. J.、Lee, H. K.、Lee, J.、Suh, H. W.(2003)。Effect of ginsenoside Rd on nitric oxide system induced by lipopolysaccharide plus TNF-alpha in C6 rat glioma cells。Arch Pharm Res,26,375-382。  new window
107.Matsuda, H.、Kageura, T.、Morikawa, T.、Toguchida, I.、Harima, S.、Yoshikawa, M.(2000)。Effects of stilbene constituents from rhubarb on nitric oxide production in lipopolysaccharide-activated macrophages。Bioorg Med Chem Lett,10,323-327。  new window
108.Yao, Y.、Hausding, M.、Erkel, G.、Anke, T.、Forstermann, U.、Kleinert, H.(2003)。Sporogen, S14-95, and S-curvularin, three inhibitors of human inducible nitric-oxide synthase expression isolated from fungi。Mol Pharmacol,63,383-391。  new window
109.Du, Z. Y.、Li, X. Y.(1998)。Effects of ginkgolides on interleukin-1, tumor necrosis factor-alpha and nitric oxide production by rat microglia stimulated with lipopolysaccharides in vitro。Aizneimittelforschung,48,1126-1130。  new window
110.Du, Z. Y.、Li, X. Y.(1998)。Inhibitory effects of ginkgolides on nitric oxide production in neonatal rat microglia in vitro。Zhongguo Yao L i Xue Bao,19,467-470。  new window
111.Zhao, H. W.、Li, X. Y.(1999)。Ginkgolide A, B, and huperzine A inhibit nitric oxide production from rat C6 and human BT325 glioma cells。Zhongguo Yao L i Xue Bao,20,941-943。  new window
112.Zhou, H. F.、Niu, D. B.、Xue, B.、Li, F. Q.、Liu, X. Y.、He, Q. H.、Wang, X. H.、Wang, X. M.(2003)。Triptolide inhibits TNF-alpha, IL-1 beta and NO production in primary microglial cultures。Neuroreport,14,1091-1095。  new window
113.Aoki, S.、Ye, Y.、Higuchi, K.、Takashima, A.、Tanaka, Y.、Kitagawa, I.、Kobayashi, M.(2001)。Novel neuronal nitric oxide synthase (nNOS) selective inhibitor, aplysinopsin-type indole alkaloid, from marine sponge Hyrtios erecta。Chem Pharm Bull,49,1372-1374。  new window
114.Kumagai, Y.、Nakajima, H.、Midorikawa, K.、Homma-Takeda, S.、Shimojo, N.(1998)。Inhibition of nitric oxide formation by neuronal nitric oxide synthase by quinones: nitric oxide synthase as a quinone reductase。Chem Res Toxicol,11,608-613。  new window
115.Tang, W.、Sun, X.、Fang, J. S.、Zhang, M.、Sucher, N. J.(2004)。Flavonoids from Radix Scutellariae as potential stroke therapeutic agents by targeting the second postsynaptic density 95 (PSD-95)/disc 1 arge/zonula o ccludens-1 (PDZ) domain of PSD-95。Phytomedicine,11,277-284。  new window
116.Kim, Y. C.、Kim, S. R.、Markelonis, G. J.、Oh, T. H.(1998)。Ginsenosides Rbl and Rg3 protect cultured rat cortical cells from glutamate-induced neurodegeneration。J Neurosci Res,53,426-432。  new window
117.Liu, J. G.、Li, R.、Liu, G. Q.(1999)。1-S.R-daurisoline protects cultured hippocampal neurons against glutamate neurotoxicity by reducing nitric oxide production。Zhongguo Yao L i Xue Bao,20,21-26。  new window
118.Kaneko, S.、Maeda, T.、Kume, T.、Kochiyama, H.、Akaike, A.、Shimohama, S.、Kimura, J.(1997)。Nicotine protects cultured cortical neurons against glutamate-induced cytotoxicity via alpha7-neuronal receptors and neuronal CNS receptors。Brain Res,765,135-140。  new window
119.Zhao, H. W.、Li, X. Y.(2002)。Ginkgolide A, B, and huperzine A inhibit nitric oxide-induced neurotoxicity。Int Immunopharmacol,2,1551-1556。  new window
120.Zou, Y.、Kim, A. R.、Kim, J. E.、Choi, J. S.、Chung, H. Y.(2002)。Peroxynitrite scavenging activity of sinapic acid (3,5-dimethoxy-4-hydroxycinnamic acid) isolated from Brassica juncea。J Agric Food Chem,50,5884-5890。  new window
121.Yokozawa, T.、Ishida, A.、Kashiwada, Y.、Cho, E. J.、Kim, H. Y.、Ikeshiro, Y.(2004)。Coptidis Rhizoma: protective effects against peroxynitrite-induced oxidative damage and elucidation of its active components。J Pharm Pharmacol,56,547-556。  new window
122.Kim, A. R.、Zou, Y. N.、Park, T. H.、Shim, K. H.、Kim, M. S.、Kim, N. D.、Kim, J. D.、Bae, S. J.、Choi, J. S.、Chung, H. Y.(2004)。Active components from Artemisia iwayomogi displaying ONOO(-) scavenging activity。Phytother Res,18,1-7。  new window
123.Bastianetto, S.、Zheng, W. H.、Quirion, R.(2000)。Neuroprotective abilities of resveratrol and other red wine constituents against nitric oxide-related toxicity in cultured hippocampal neurons。Br J Pharmacol,131,711-720。  new window
124.Song, W.、Guan, H. J.、Zhu, X. Z.、Chen, Z. L.、Yin, M. L.、Cheng, X. F.(2000)。Protective effect of bilobalide against nitric oxideinduced neurotoxicity in PC12 cells。Acta Pharmacol Sin,21,415-420。  new window
125.Soung, D. Y.、Rhee, S. H.、Kim, J. S.、Lee, J. Y.、Yang, H. S.、Choi, J. S.、Yokozawa, T.、Han, Y. N.、Chung, H. Y.(2003)。Peroxynitrite scavenging activity of lithospermate B from Salvia miltiorrhiza。J Pharm Pharmacol,55,1427-1432。  new window
126.Pannala, A. S.、Razaq, R.、Halliwell, B.、Singh, S.、Rice-Evans, C. A.(1998)。Inhibition of peroxynitrite dependent tyrosine nitration by hydroxycinnamates: nitration or electron donation?。Free Radic Biol Med,24,594-606。  new window
127.Piao, H. Z.、Jin, S. A.、Chun, H. S.、Lee, J. C.、Kim, W. K.(2004)。Neuroprotective effect of wogonin: potential roles of inflammatory cytokines。Arch Pharm Res,27,930-936。  new window
128.Suzuki, M.、Tabuchi, M.、Ikeda, M.、Umegaki, K.、Tomita, T.(2004)。Protective effects of green tea catechins on cerebral ischemic damage。Med Sci Monit,10,BR166-BR174。  new window
129.Feiriero, D. M.、Sheldon, R. A.、Black, S. M.、Chuai, J.(1995)。Selective destruction of nitric oxide synthase neurons with quisqualate reduces damage after hypoxia-ischemia in the neonatal rat。Pediatr Res,38,912-918。  new window
130.Suuronen, T.、Huuskonen, J.、Pihlaja, R.、Kyrylenko, S.、Salminen, A.(2003)。Regulation of microglial inflammatory response by histone deacetylase inhibitors。J Neurochem,87,407-416。  new window
131.Hou, R. C.、Chen, H. L.、Tzen, J. T.、Jeng, K. C.(2003)。Effect of sesame antioxidants on LPS-induced NO production by BV2 microglial cells。Neuroreport,14,1815-1819。  new window
132.Kim, J. E.、Kim, A. R.、Chung, H. Y.、Han, S. Y.、Kim, B. S.、Choi, J. S.(2003)。In vitro peroxynitrite scavenging activity of diarylheptanoids from Curcuma longa。Phytother Res,17,481-484。  new window
133.Rodriguez, J.、Quignard, J. F.、Fagni, L.、Lafon-Cazal, M.、Bockaert, J.(1994)。Blockade of nitric oxide synthesis by tyrosine kinase inhibitors in neurones。Neuropharmacology,33,1267-1274。  new window
134.Stevens, J. F.、Miranda, C. L.、Wolthers, K. R.、Schimerlik, M.、Deinzer, M. L.、Buhler, D. R.(2002)。Identification and in vitro biological activities of hop proanthocyanidins: inhibition of nNOS activity and scavenging of reactive nitrogen species。J Agric Food Chem,50,3435-3443。  new window
135.Lee, H. H.、Yang, L. L.、Wang, C. C.、Hu, S. Y.、Chang, S. F.、Lee, Y. H.(2003)。Differential effects of natural polyphenols on neuronal survival in primary cultured central neurons against glutamate- and glucose deprivation-induced neuronal death。Brain Res,986,103-113。  new window
136.Choi, J. Y.、Park, C. S.、Kim, D. J.、Cho, M. H.、Jin, B. K.、Pie, J. E.、Chung, W. G.(2002)。Prevention of nitric oxide-mediated 1-methyl-4-phenyl-1,2, 3,6-tetrahydropyridine-induced Parkinson's disease in mice by tea phenolic epigallocatechin 3-gallate。Neurotoxicology,23,367-374。  new window
137.Bastianetto, S.、Quirion, R.(2002)。Natural extracts as possible protective agents of brain aging。Neurobiol Aging,23,891-897。  new window
138.Prast, H.、Philippu, A.(2001)。Nitric oxide as modulator of neuronal function。Progress in Neurobiology,64,51-68。  new window
 
 
 
 
第一頁 上一頁 下一頁 最後一頁 top
QR Code
QRCODE