The purpose of this report is to present the nursing experience of a stroke patient and his primary caregiver, Focused on the physical, mental and social overload of primary caregiver. During the nursing period, the author is primary nurse of patient. Using the concept of management, Data was collected by clinical observation, interviewing and listening. Through directing care of patient, major health problems of the subject were found, such as caregiver role strain, impaired of communication, ineffective of family coping and social isolation. During the nursing process, The author not only used honest acceptance, no critical attitude but also build good relationship and trust with subject, to provide suitable nursing information assisting the subject to face herself problem, develop the caring skill and positively play the role of long-term caregiver.