空氣懸浮菌落過高將嚴重影響室內空氣品質(I.A.Q.)，導致疾病防疫與感控困難。活化的二氧化氯溶液是兼具氣體與液體消毒能力的環保消毒劑，本研究蒐整其理化特性與消毒機制的相關文獻，並執行200-1000 ppm 二氧化氯氣霧在實驗室、醫院與議場中的室內懸浮菌落消毒效能研究。結果顯示活化後的200ppm、250ppm 與1000ppm 二氧化氯溶液，分別以超音波震盪方式，釋放4.0mL/m3、2.5mL/m3 與1.0mL/m3 的氣霧在各類室內空間，均能有效消除空氣懸浮菌落，平均滅菌率為94.4%；唯室內空間的密閉性、菌落數、人員數、二氧化氯停留時間與空調系統均能影響消毒效能；經實場操作獲得30分鐘後達九成消毒率的濃度與釋放量的參考乘積為625 ppm．mL/m3，該經驗值可提供日後室內空氣消毒規劃依據。

Excess amount of bacteria colonies suspended in indoor air space severely affect indoor air quality (I.A.Q.), which leads to difficulties in epidemic prevention and infection control. Chlorine dioxide is a disinfectant which maintains its disinfection capability both in gas and solution states. In this study we collected relevant references about the physicochemical properties and the disinfection mechanisms of chlorine. Moreover, we further conducted the investigation of the disinfection effect of 200-1000 ppm chlorine dioxide fog in the indoor air of laboratories, hospitals and conference rooms. Activated chlorine dioxide solution of 200 ppm, 250 ppm and 1000 ppm were released by using ultrasonic machine with various amount, 4.0 mL/m3, 2.5 mL/m3 and 1.0 mL/m3 into different indoor spaces. We found that chlorine dioxide vapor can effectively disinfect the suspended bacteria colonies, resulted in an average disinfection rate of 94.4 %. However, factors such as the closeness, original bacteria colonies, staff number, contact time and circulation of personnel can affect the disinfection efficiency. We concluded the product of concentration and release amount should be 625 ppm．mL/m3 to reach the disinfection rate of 90 % in 30 minutes. This experimental number can serve as a reference to future use of indoor air disinfection.