This paper described the process of assisting two pupils with severe cerebral palsy in inclusive classroom to participate learning activities by using computer. The authors adopted learning activities based approach to implement the interventions. The procedure included four major steps: needs and capability assessment, position and access evaluation, access devices and learning devices selection, and integration preparing. Based on the result of intervention, authors found that providing students with serve cerebral palsy with systematic intervention could assist them to participate in the general education curriculum.