This paper discusses a nursing experience for the physical and mental disturbance of a patient who suffer from stage II oral cancer and faced wide excision, radical neck dissection, partial mandibular excision and local flap plasty. The author assessed the client by means of Gordon 11 healthy function evaluation tool. Data collected through interviews, observation, listening, and direct care. Finding out the chief healthy problem including anxiety, acute pain, potential infection, nervousness of the care giver, body image disturbance. During this periods, we gain trust and support of the patient with his family through establishment or nurse-patient relationship. The author applied caring, non-criticized attitude, encouraging patient to express emotion, supply individual and general nursing, Through these approach to help client release anxiety, improving pain after operation, removing tube under non-infective situation and improving healing of oral and cervical wounds, increasing assurance of client, re-establish positive self-recognition, learning self-care and assisting his wife to resolve potential pressure problem. We hope to the care report to provide nursing professionals with a source of reference for healthcare quality improvement.