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題名:低氧環境與氧化壓力
書刊名:中華體育季刊
作者:陸康豪謝伸裕 引用關係林嘉志 引用關係
出版日期:2009
卷期:23:1=88
頁次:頁1-9
主題關鍵詞:活性氧氧化壓力低氧低氧再充氧
原始連結:連回原系統網址new window
相關次數:
  • 被引用次數被引用次數:期刊(4) 博士論文(0) 專書(0) 專書論文(0)
  • 排除自我引用排除自我引用:4
  • 共同引用共同引用:8
  • 點閱點閱:33
激烈運動可產生過量的活性氧化物(reactive oxygen species, ROS),並破壞人體內氧化壓力與抗氧化系統間的平衡關係,對細胞、組織造成累積性的氧化傷害,而低氧環境已被證實爲誘導人體產生ROS的刺激源。研究證據顯示人體或動物在低氧環境下,血液或骨骼肌等部位脂質過氧化指標(如:TBARS)、蛋白質氧化傷害指標(如:羰基化蛋白質)及氧化態/還原態麩胱甘肽(如:GSSG/GSH)比例均隨著氧氣分壓的下降而增加,而超氧離子歧化酶活性則會下降。因此,不論是進行攀登高山活動或是運動員進行高地訓練時,除了要注意高山症之外,也不能忽視ROS造成的氧化壓力。此外,由低氧再回復到常氧環境時,紅血球與肌肉的氧化壓力也會顯著增加。暴露於低氧環境時,服用適量的抗氧化劑可能有助於清除體內的ROS,減緩人體所承受的氧化壓力。
期刊論文
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4.林嘉志、姚承義、陸康豪(20080600)。硫辛酸增補對運動的可能效益。中華體育季刊,22(2)=85,24-33。new window  延伸查詢new window
5.Ji, L. L.(1999)。Antioxidants and oxidative stress in exercise。Proceedings of the Society for Experimental Biology and Medicine,222(3),283-292。  new window
6.Maiti, P.、Singh, S. B.、Sharma, A. K.、Muthuraju, S.、Banerjee, P. K.、Ilavazhagan, G.(2006)。Hypobaric hypoxia induces oxidative stress in rat brain。Neurochemistry International,49(8),709-716。  new window
7.趙善民、黃俊傑、黃麗娟、晉玲、何顯教、梁祥仁(2004)。寒冷和低氧條件 下家兔的血液流變學及自由基的改變。中國血液流變學雜誌,14(1),57-58。  延伸查詢new window
8.袁建琴、徐勇、潘同斌、王瑞元(2005)。低氧、離心力竭運動對骨骼肌自由基代謝的影響。武漢體育學院學報,39(5),40-43。  延伸查詢new window
9.趙偉民、康龍麗(2002)。不同海拔不同民族人群機體自由基代謝的比較。西藏大學學報,17(3),11-12。  延伸查詢new window
10.Dosek, A.、Ohno, H.、Acs, Z.、Taylor, A. W.、Radak, Z.(2007)。High altitude and oxidative stress。Respiratory Physiology & Neurobiology,158(2/3),128-131。  new window
11.Gonzalez, G.、Celedon, G.、Escobar, M.、Sotomayor, C.、Ferrer, V.、Benitez, D.(2005)。Red cell membrane lipid changes at 3,500 m and on return to sea level。High Altitude Medicine & Biology,6(4),320-326。  new window
12.Jefferson, J. A.、Simoni, J.、Escudero, E.、Hurtado, M. E.、Swenson, E. R.、Wesson, D. E.(2004)。Increased oxidative stress following acute and chronic high altitude exposure。High Altitude Medicine & Biology,5(1),61-69。  new window
13.Harman, D.(2003)。The free radical theory of aging。Antioxidants & Redox Signaling,5(5),557-561。  new window
14.Sentürk, U. K.、Gundiiz, F.、Kuru, O.、Koçer, G.、Ozkaya, Y. G.、Yesilkaya. A.、Bor-Kucukatay, M.、Uyuklu, M.、Yalcin, O.、Baskurt, O. K.(2005)。Exercise-induced oxidative stress leads hemolysis in sedentary but not trained humans。Journal of Applied Physiology,99(4),1434-1441。  new window
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16.Khan, S.、O'Brien, P. J.(1995)。Modulating hypoxia-induced hepatocyte injury by affecting intracellular, redox state。Biochimica et Biophysica Acta,1269(2),153-161。  new window
17.Knez, W. L.、Coombes, J. S.、Jenkins, D. G.(2006)。Ultra-endurance exercise and oxidative damage: Implications for cardiovascular health。Sports Medicine,36(5),429-441。  new window
18.Magalhaes, J.、Ascensao, A.、Viscor, G.、Soares, J. M.、Oliveira, J.、Marques, F.(2004)。Oxidative stress in humans during and after 4 hours of hypoxia at a simulated altitude of 5500 m. Aviation。Space, and Environmental Medicine,75(1),16-22。  new window
19.Magalhaes, J.、Ascensao, A.、Soares, J. M.、Ferreira, R.、Neuparth, M. J.、Marques, F.(2005)。Acute and severe hypobaric hypoxia increases oxidative stress and impairs mitochondrial function in mouse skeletal muscle。Journal of Applied Physiology,99(4),1247-1253。  new window
20.Magalhaes, J.、Ascensao, A.、Soares, J. M.、Ferreira, R.、Neuparth, M. J.、Oliveira, J.(2005)。Acute and chronic exposition of mice to severe hypoxia: The role of acclimatization against skeletal muscle oxidative stress。International Journal of Sports Medicine,26(2),102-109。  new window
21.Magalhaes, J.、Ascensao, A.、Soares, J. M.、Neuparth, M. J.、Ferreira, R.、Oliveira, J.(2004)。Acute and severe hypobaric hypoxia-induced muscle oxidative stress in mice: The role of glutathione against oxidative damage。European Journal of Applied Physiology,91(2/3),185-191。  new window
22.Magalhaes, J.、Ferreira, R.、Neuparth, M. J.、Oliveira, P. J.、Marques, F.、Ascensao, A.(2007)。Vitamin E prevents hypobaric hypoxia-induced mitochondrial dysfunction in skeletal muscle。Clinical Science,113(12),459-466。  new window
23.Nakanishi, K.、Tajima, F.、Nakamura, A.、Yagura, S.、Ookawara, T.、Yamashita, H.(1995)。Effects of hypobaric hypoxia on antioxidant enzymes in rats。The Journal of Physiology,489(3),869-876。  new window
24.Subudhi, A. W.、Jacobs, K. A.、Hagobian, T. A.、Fattor, J. A.、Fulco, C. S.、Muza, S. R.(2004)。Antioxidant supplementation does not attenuate oxidative stress at high altitude。Aviation, Space, and Environmental Medicine,75(10),881-888。  new window
25.Radak, Z.、Asano, K.、Lee, K. C.、Ohno, H.、Nakamura, A.、Nakamoto, H.(1997)。High altitude training increases reactive carbonyl derivatives but not lipid peroxidation in skeletal muscle of rats。Free Radical Biology & Medicine,22(6),1109-1114。  new window
26.Radak, Z.、Lee, K.、Choi, W.、Sunoo, S.、Kizaki, T.、Oh-ishi, S.(1994)。Oxidative stress induced by intermittent exposure at a simulated altitude of 4.000 m decreases mitochondrial superoxide dismutase content in soleus muscle of rats。European Journal of Applied Physiology and Occupational Physiology,69(5),392-395。  new window
27.Vij, A. G.、Dutta, R.、Satija, N. K.(2005)。Acclimatization to oxidative stress at high altitude。High Altitude Medicine & Biology,6(4),301-310。  new window
圖書
1.Wilmore, J. H.、Costill, D. L.、Kenney, W. L.(2008)。Physiology of sport and exercise。Human Kinetics。  new window
2.Armstrong, L. E.(2000)。Performing in extreme environments。Champaign, IL:Human Kinetics。  new window
3.Powers, Scott K.、Howley, Edward T.(2004)。Exercise physiology: Theory and application to fitness and performance。McGraw-Hill。  new window
 
 
 
 
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