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題名:運動對高密度脂蛋白代謝與膽固醇逆向運輸之影響
書刊名:中華體育季刊
作者:黃依婷
出版日期:2009
卷期:23:4=91
頁次:頁9-17
主題關鍵詞:高密度脂蛋白膽固醇膽固醇逆向運輸
原始連結:連回原系統網址new window
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  • 被引用次數被引用次數:期刊(1) 博士論文(0) 專書(0) 專書論文(0)
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  • 點閱點閱:98
要研究證實規律運動能增加血漿高密度脂蛋白(high-density lipoprotein, HDL)濃度,降低心血管疾病的風險。HDL的循環在體內膽固醇的代謝上扮演著極重要的角色。膽固醇逆向運輸(reverse transport of cholesterol, RCT)即HDL生成、循環於體內並運輸膽固醇及脂肪至肝臟代謝的過程。運動改變HDL濃度,背後意義來自於RCT 機制中參與的蛋白質如膽固醇脂轉運蛋白(cholesteryl ester transfer protein, CETP)與卵磷脂醯基轉移酶(lecithin cholesterol acyltransferase, LCAT)、肝脂解酶(hepatic lipase, HL)、脂蛋白脂解酶 (lipoprotein lipase, LPL)等酵素活性表現的改變,使得膽固醇從周邊細胞中流出(efflux)以及HDL成熟的速率加快,進而更有效率的清除體內多餘的膽固醇,降低因膽固醇堆積而引起的動脈粥狀硬化等慢性心血管疾病。
期刊論文
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圖書
1.Nelson, D. L.、Cox, M. M.(2005)。Principles of Biochemistry。New York, NY:W. H. Freeman and Company。  new window
 
 
 
 
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