The aticle exploring the professional relationship between drug abuse prevention and social work. And understanding the function of social work in the drug abuse prevention professional field. The first, knowing the characteristics and types about drug. Secondly, exploring drug abuse contents (including the drug abuse crime seriously, drug addiction reasons and negative behabior). The third, the contents about drug abuse prevention and social work. The aticle suggestions have 2 dimensions: The first dimension, being four systems (including the social work Licentiate in the government, cross professional workers partner etc).The secondly dimension, being practical , having 4 approaches (including the drug abuse prevention and social work profession, drug abuser , drug abuser’s family, drug abuser’s school and social environment) and 12 practical items.