The purpose of this study was to examine the differences in kinematics of basketball shooting between different ball sizes at two distinct distances. Participants were 8 college women basketball players, in average age of 21±1.20 years old, 172.12±5.04cm in height and 63.25±6.26Kg in weight. Shootings with different ball sizes (size No.6, size No.7), at the distances of free-throw line and three-point lines, were filmed by a high-speed digital camera with speed of rate 250Hz and shutter of 1/1000, as well as two other digital cameras. The differences of kinematic parameters, including release speed, release angle, release height, the apex of projection and incidence angle, were further verified by the dependent-sample t test. The findings were as follow:1. No difference was found in release angle while shooting with two different balls at the free-throw line. Contrarily, the distinction of release angle between two different balls was reported at the three- point line. The angle of size No.6 was steeper than that of size No.7, which might relate to the reduction of muscle load.2. The difference in release height between two balls was found at the free-throw line. The height of size No.6 was higher than that of size No.7, which might result from a change in arm movement accompanied with the decrement of ball weight. Besides, no difference was found in release height at the three-point line.3. The differences in release velocity, the apex of projection, and incidence angle, were not reported between two different ball sizes at these two distances. Therefore, the reduction of ball sphericity was not enough to affect these three kinematic parameters of shooting.In conclusion, an alteration in shooting movement due to a change of ball size was found. The development of new defensive strategies will be necessary for women basketball players to benefit from their games.