Since the 1970s, Image Maximum Theater (referred to as IMAX Theater or Giant Screen Theater) has been used as an educational instrument by science museums. Hundreds of museums around the world have established giant screen theaters. However, little research has been conducted on giant screen theater-related issues. In this study, the concepts and methods of front-end evaluation were employed to examine the issues regarding film selection for giant screen theaters in science museums, with the IMAX Theater of the National Science and Technology Museum (NSTM) serving as an example. Interviews, focus groups and questionnaires were used to collect data from volunteers working in the theaters, frequent visitors and IMAX film viewers. From qualitative and quantitative data analyses, the major findings are as follows: 1. Audiences prefer films that are educational, entertaining and experiential. On the other hand, they dislike films in which the story is unclear or incomplete or that are too short or that lack educational inspiration or experiential features. 2. Among a total of 10 films that were included in the study, four are recommended. They are: The Ultimate Wave: Tahiti 3D, Legends of Flight, Grand Canyon Adventure: River at Risk 3D and Fly Me to the Moon. 3. Three categories of factors should be taken into account when selecting films for science museum giant screen theaters. They are the features of the film, features and operating strategy of the museum and external factors.