This article describes the nursing care experience and rehabilitation process of an osteoarthritis patient who accepted total knee replacement surgery. The nursing period was from June 13th to 18th, 2010. The author used Gordon's 11 Functional Health Pattern assessments and discovered four heath problems through observation, conversation, and health evaluation. The four health problems were as follows: anxiety, postoperative pain, dysfunction in exercising, and sleeping disorder. During the nursing period, the author provided relevant information together with postoperative nursing guidelines, and dealt with the health problems enabling the patient to face the disease with courage and to participate in appropriate rehabilitation treatment, not only dealing with health problems, but also helping the patient to recover the ability of daily activities and achieve better health adjustment.