Signage provides very useful supplement information for a variety of areas and facilities. Signage can be viewed as a guide in a specific location. It is crucial to incorporate the environmental space along with its related text and graphics in the design and such design should be based on the user-center as the guiding principal. As such the signage can be extended outward to the environment space and vice verse the environment space information can be extend inward back to human through signage. This report is based from the research of information collection as the starting point. It attempts to categorize and organize, the existing literatures which is available domestically and/or internationally, and the design principles and concepts in the areas of wayfinding, signage and information design. In addition, this paper also analyzed the existing signage design in Taiwan's International Airport (TPE Airport) and conducted studies in many designs from famous foreign international airports. Using the inductive and deductive methods, the author concluded the paper with a proposal in signage system design principles. As a result, such signage system design principles can be applied to improve the current signage system in Taiwan's International Airport toward a more user-centered environment. The design process presented in this paper may also be used as a reference for future signage system design and follow-up studies and be applied for design toward other types of public spaces and/or buildings.