Dementia is characterized by decreased cognitive functions beyond normal aging, usually associated with behavioral disturbance and other mental health disorders. In Taiwan, the prevalence of dementia becomes higher, resulting in a huge and negative impact on personal health. The "mini mental state examination (MMSE)" is commonly used for screening cognitive function. The MMSE provides measures of orientation, registration (immediate memory), short-term memory (but not long-term memory) as well as language functioning, which can be used to indicate the presence of cognitive impairment, such as in a person with suspected dementia. This research applies Kinect motion-sensing technology and voice guidance to develop K-Box, an interactive training system for seniors. Through answering questions designed based on the 5 core dimensions suggested by the MMSE using body motions, this system aims to maintain the active lifestyle for seniors as well as to reduce the risk of developing dementia. To respond to the declines physical and sensory capabilities of seniors, K-Box provides a natural user interface that allows seniors to interact intuitively, and is easy and friendly to operate. Pre- recorded messages by the children and family members are used in the voice guidance to provide positive feedback and motivation to the seniors for using the system.