This study explores the relationship between yoga exercise participants' quality of life and sexual satisfaction. The research subjects were selected from a Yoga center in Taipei and asked to complete the questionnaire. The total samples conducted were 450 samples, with a 93.33% recovery rate. 420 questionnaires were analyzed by descriptive statistics, factor analysis, independent t-test, one-way ANOVA and multiple regression analysis. There are four key findings:First, the majority of yoga exercise participants are females, fixed sexual couples for the majority. The most popular yoga course was Hatha-yoga. Second, males' setting attribute of sexual attitude is more significant than females. The fixed sexual couples' attributes are quality of life and sexual satisfaction. Third, different personal backgrounds affected the yoga exercise participants' quality of life and sexual satisfaction. Fourth, the yoga exercise participants' quality of life and sexual satisfaction are positively correlated. There is higher sexual satisfaction when the body is healthier. In conclusion, yoga exercise not only improves body shape and develop new social networks but increases the quality of life and sexual satisfaction. Therefore, related departments such as governments and yoga institutions should popularize this fact.