Objectives: In this study, we intended to validate the Ruminative Response Scale-Chinese version (RRS-C), a measure of rumination that has been translated and used to evaluate the intensity of ruminative responses in clinically depressed patients in Taiwan, as well as to examine the factor structure of the RRS-C and determined cut-off scores for identifying patients with prominent rumination tendencies. Methods: We recruited study participants from day care centers or clinics of several hospitals in Taiwan. Study instruments included the RRS-C, Beck Depression Inventory-II, as well as Activity Participation and Restriction Questionnaire. Results: Totally 143 participants were enrolled in this study. Three factors, ＂symptom-based rumination,＂ ＂isolation/introspection,＂ and ＂analyzing to understand,＂ were labeled for the RRS-C, and two factors, ＂brooding,＂ and ＂refl ection,＂ for the brief RRS-C. Values of Cronbach's alpha for the factors were ranged from acceptable to excellent. Conclusion: The RRS-C has acceptable validity and reliability to be applied on depressed Taiwanese patients for screening and diagnosis. This scale has also been demonstrated the potential and value to detect depressed patients with high rumination tendency and those who suffer from not well engaging daily activities in Taiwan.