In the mid-seventeenth century, the Ming Dynasty was overthrown, and Manchus came to the throne of China. Shunzhi was a young emperor, who was the first entered Peking to rule the Qing Dynasty .In same time, the fifth Dalai Lama of Gelugpa school was just became a religious leader of Tibet, through Mongolian Khoshut Khan military forces. During this period, meet of these two leaders in Peking was able to represent a significant figure of history. The fifth Dalai Lama was invited by Qing court and departed from the Drepung Monastery in Lhasa of Tibet in March 1652, left Peking in February 1653, returned to Lhasa in October. How to treat the fifth Dalai Lama to Peking was a complex issue in Qing court, from reception to Peking along the way, and donated the fifth Dalai Lama titles, etc. Through different views towards the Manchu, Mongolian, Chinese ministers and priests of Jesus discussed in Qing court, the policy of treatment was finally made. In addition to determining the relationship of Qing Dynasty’s suzerainty over Tibet, the more time it was appeared the Manchu, Mongolian, Tibetan, and Han nationalities interacted in political, religious, cultural, and economic, along with in Chinese and Western cultural interaction.