The purpose of this research was understand the relations among job stress, leisure coping and well-being of stuffs of Ministry of Foreign Affairs. The research took 204 stuffs as the research subjects for the survey. According to the data collected from questionnaire, descriptive statistics, Person's correlation coefficients, and multiple line regression analysis were performed for data analysis. The results were derived as following: the male as the same female and ages were between 41-50 years old and education level above university (college) and they were above junior officer not supervisor. There was negative correlation among stuffs' job stress and well-being. There was positive correlation among stuffs' leisure coping and well-being. Finally, the job stress, leisure coping were predictors for well-being.