This article describes the nursing experience of a 43-year-old female patient with malignant thymoma and myasthenia gravis. Information was collected via direct nursing, observation, written communication, physical examination, and chart review from October 13, 2012 to October 31, 2012. Gordon 11 Function Health Patterns for complete evaluation was used. Problems identified included ineffective breathing patterns, malnutrition, and feelings of hopelessness. A relationship of trust was built through caring, companionship, and listening. Respiratory rehabilitation exercises were provided to improve ventilation, to maintain oxygenation status and to relieve physical discomfort. High-calorie and high-protein diets were provided to improve nutrition. Health education manuals were used to describe disease progression, while the family members were invited to participate in treatment-linked support networks combining with interdisciplinary resource management to help the patient readily accept needed treatments. This article shares the experiences of caring for the physical and psychological needs of female malignant thymoma patients with myasthenia gravis and demonstrates how family support systems can encourage patients to receive treatments and fight against malignancy.