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題名:室外空氣汙染物與學齡前兒童首發氣喘之關聯,2007~2011年
書刊名:臺灣公共衛生雜誌
作者:鍾慧穎謝佳容 引用關係曾俊傑尹立銘 引用關係
作者(外文):Chung, Hui-yingHsieh, Chia-jungTseng, Chun-chiehYiin, Lih-ming
出版日期:2016
卷期:35:2
頁次:頁199-208
主題關鍵詞:全民健康保險資料庫學齡前兒童氣喘空氣汙染物交通排放National health insurance research databasePre-school childrenAsthmaAir pollutantsTransportation exhaust
原始連結:連回原系統網址new window
相關次數:
  • 被引用次數被引用次數:期刊(1) 博士論文(0) 專書(0) 專書論文(0)
  • 排除自我引用排除自我引用:1
  • 共同引用共同引用:15
  • 點閱點閱:18
目標:探討近年來全台灣0-6歲兒童氣喘首次發生率,與環境監測之空氣汙染物濃度的關係。方法:以2007年至2011年之全民健康保險研究資料庫承保抽樣歸人檔40萬人,依據國際疾病分類法第九版(ICD-9-CM)診斷碼,篩選6歲以下第一次發生氣喘兒童為研究對象,並使用2006與2011年間環保署空氣品質監測數據PM_(10)、SO_2、NO_X(NO及NO_2)、CO及O_3之濃度資料,探究首發氣喘與空氣汙染物之相關性。結果:室外的空氣汙染物,以NO_X、CO與學齡前兒童首次氣喘發病關聯性顯著(ρ > 0.5),而此二者間相關性也高於其他任何汙染物種間的關聯(ρ = 0.892),推測NO_X及CO主要來源為交通排放。進一步以多變項邏輯斯迴歸分析,發現暴露於高濃度NOX(> 16.3 ppb)導致氣喘發病比低濃度具有顯著勝算比,最高可達1.45(95%CI: 1.13- 1.86)。由於並無直接證據顯示NO_X、CO可導致氣喘,因此推論台灣學齡前兒童的氣喘首發率,應與交通排放汙染物相關。結論:交通排放汙染物與氣喘發病相關性高,建議民眾做好個人防護,並時時注意空氣品質資訊,以降低學齡前兒童氣喘發病機率。
Objectives: This study determined the incidence of the first occurrence of asthma in preschool children (0-6 years of age), and the relationship to air pollutants. Methods: Based on the Longitudinal National Health Insurance database (n=400,000) from 2007-2011, the study identified eligible asthmatic subjects in accordance with the 9th version of the international disease classification (ICD-9-CM), and used the local environmental monitoring data of PM_(10), SO_2, NO_X (NO and NO_2), CO, and O_3 from the Environmental Protection Administration (EPA) to relate to the first incidence of asthma for the eligible subjects. Results: Among the air pollutants, NO_X and CO were significantly associated with asthma, and were highly correlated with each other (ρ = 0.892), suggesting that NO_X and CO should have originated from transportation exhaust. The multivariate logistic regression analyses showed that high levels of NOX (> 16.3 ppb) resulted in significant odds ratios of asthma exacerbation up to 1.45 (95% CI: 1.13 - 1.86) compared to low levels. Because of no direct evidence showing that NOX or CO triggered asthma, it is suggested that the first incidence of asthma in pre-school children is related to transportation exhaust. Conclusions: Asthma in pre-school children was significantly associated with transportation exhaust. It is recommended that attention should be paid to personal care and information of air quality to lower the chances of asthma occurrence for preschool children.
期刊論文
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11.張立德、林佑蓉、唐進勝(20060600)。臺北縣八鄉鎮國小學童氣喘盛行率之調查。輔仁醫學期刊,4(2),61-72。  延伸查詢new window
12.Debley, J. S.、Redding, G. J.、Critchlow, C. W.(2004)。Impact of adolescence and gender on asthma hospitalization: a population-based birth cohort study。Pediatr Pulmonol,38,443-450。  new window
13.Anderson, H. R.、Ponce de Leon, A.、Bland, J. M.、Bower, J. S.、Emberlin, J.、Strachan, D. P.(1998)。Air pollution, pollens, and daily admissions for asthma in London 1987-1992。Thorax,53,842-848。  new window
14.Atkinson, R. W.、Anderson, H. R.、Strachan, D. P.、Bland, J. M.、Bremmer, S. A.、Ponce de Leon, A.(1999)。Short-term associations between outdoor air pollution and visits to accident and emergency departments in London for respiratory complaints。Eur Respir J,13,257-265。  new window
15.Brauer, M.、Hoek, G.、Van Vliet, P.(2002)。Air pollution from traffic and the development of respiratory infections and asthmatic and allergic symptoms in children。Am J Respir Crit Care Med,166,1092-1098。  new window
16.Gehring, U.、Wijga, A. H.、Brauer, M.(2010)。Traffic-related air pollution and the development of asthma and allergies during the first 8 years of life。Am J Respir Crit Care Med,181,596-603。  new window
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21.Alexis, N. E.、Carlsten, C.(2014)。Interplay of air pollution and asthma immunopathogenesis: a focused review of diesel exhaust and ozone。Int Immunopharmacol,23,347-355。  new window
22.Brandt, E. B.、Biagini Myers, J. M.、Acciani, T. H.(2015)。Exposure to allergen and diesel exhaust particles potentiates secondary allergen-specific memory responses, promoting asthma susceptibility。J Allergy Clin Immunol,136,295-303。  new window
23.Zhang, J. J.、McCreanor, J. E.、Cullinan, P.(2009)。Health effects of real-world exposure to diesel exhaust in persons with asthma。Res Rep Health Eff Inst,138,5-109。  new window
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研究報告
1.葛應欽、黃吉志、趙玉英(1997)。空氣品質與學童呼吸系統健康追蹤研究專案研究計畫 (計畫編號:EPA-86-FA05-09-A1)。台北:行政院環境保護署。  延伸查詢new window
圖書
1.顏有利、吳照雄(2002)。空氣品質長期趨勢分析與年報編撰。台北:行政院環境保護署。  延伸查詢new window
2.張漢昌(2012)。環境汙染危害概論。新北市:新文京開發。  延伸查詢new window
其他
1.World Health Organization(2015)。Air quality guidelines, Global update 2005, Particulate matter, ozone, nitrogen dioxide and sulfur dioxide,http://www.euro.who.int/_data/assets/pdf_file/0005/78638/E90038.pdf?ua=1, 。  new window
2.Natural Resources Defense Council(2015)。Asthma and air pollution,http://www.nrdc.org/health/effects/fasthma.asp, 2015/08/24。  new window
3.WHO(2015)。Prevention of allergy and allergic asthma,http://whqlibdoc.who.int/hq/2003/WHO_NMH_MNC„CRA_03.2.pdf?ua=1, 2015/03/05。  new window
4.台灣氣喘諮詢協會(2009)。台灣氣喘診療指引,http://www.taiwanasthma.com.tw/ download_04.htm, 2015/04/12。  延伸查詢new window
5.衛生福利部國民健康署。出生通報統計資料,http://www.hpa.gov.tw/BHPNetAVeb/HealthTopic/ TopicArticle.aspx?No=201110190004&parent id=201109200006, 2015/11/24。  延伸查詢new window
6.行政院環境保護署(2015)。交通工具空氣污染物排放標準,http://ivy5.epa.gov.tw/docfile/040160.doc, 2015/12/24。  延伸查詢new window
 
 
 
 
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