補充諾麗果對中年男性長跑運動後氧化壓力與組織傷害之影響_

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題名：	補充諾麗果對中年男性長跑運動後氧化壓力與組織傷害之影響
書刊名：	大專體育學刊
作者：	黃奕仁／侯建文／黃景耀／祁崇溥／余思賢
作者(外文)：	Huang, Yi-jen／Hou, Chieh-wen／Huang, Ching-yao／Chi, Chung-pu／Yu, Szu-hsien
出版日期：	2016
卷期：	18:4
頁次：	頁310-322
主題關鍵詞：	發炎；睪固酮；肌肉損傷；Inflammation；Testosterone；Muscle damage
原始連結：	連回原系統網址
相關次數：	被引用次數:期刊(1) 博士論文(0) 專書(0) 專書論文(0) 排除自我引用:1 共同引用:4 點閱:8

諾麗果已被發現具有抗氧化與抗發炎之功效，並於多種疾病有正面之效果。本研究之目的為探討諾麗果對於長跑運動後氧化壓力、組織傷害與分解反應之影響。本研究為交叉試驗設計，招募10名中年運動員作為受試者，分別進行對照果汁與諾麗果汁介入，介入方式為每天飲用120毫升果汁共7天，於最後一次口服介入後一天所有受試者均進行單次3小時的長跑運動，跑步距離為各受試者最佳馬拉松速度的85%。於運動前、運動後立即、後2小時與12小時抽血並分離血清進行生化分析，分析項目包含氧化壓力（丙二醛、超氧岐化酶）、發炎（介白素6）、組織損傷（肌酸激酶、天門冬氨酸轉氨酶、丙胺酸轉氨酶）與分解合成指標（睪固酮、皮質醇）。研究結果發現長跑運動後丙二醛、介白素6、肌酸激酶、皮質醇顯著上升，而睪固酮與睪固酮／皮質醇比值（T/C值）顯著降低。諾麗果介入之超氧岐化酶活性顯著高於對照組。而諾麗果介入組於運動後丙二醛濃度顯著高於對照組，但介白素6、睪固酮、睪固酮／皮質醇比率顯著低於對照組。本研究結論為雖然諾麗果可以提升抗氧化酵素活性與降低運動後發炎反應，但是應注意其增加運動後氧化傷害與降低合成反應的負面效果。

以文找文

Noni fruit (Morinda citrifolia) has been shown to possess anti-inflammatory and anti-oxidative effects. The present study aimed to investigate the influence of noni fruit juice pre-supplementation on long-distance runninginduced oxidative stress, inflammation, tissue damage and anabolic/catabolic balance in middle aged runners. In this cross-over study, 10 male subjects (aged 50.6 ± 3.0 years) were asked to complete an acute 3-hour endurance running with 85% personal best in marathon running speed. Subjects consumed the designated volume of either noni fruit juice (120 ml/day) or control juice for 7 days before the running. Blood samples were collected from both trials before, immediately, 2 h and 12 h after exercise. Changes in biomarkers, including malondialdehyde (MDA), interleukin-6 (IL-6), testosterone and cortisol levels, and activities of superoxide dismutase (SOD), creatine kinase (CK), aspartate transaminase (AST) and alanine transaminase (ALT) were analyzed. Longdistance running caused a significant increase of MDA, IL-6, CK and cortisol levels with simultaneous decrease of testosterone and testosterone/cortisol ratio (T/C ratio). Before exercise, noni fruit juice supplemented trail showed higher SOD activity than the control trial. We found higher MDA levels in noni fruit juice group, but IL-6, testosterone and T/C ratio were lower compared to the control group. In conclusion, noni fruit juice presupplementation increased the anti-oxidative enzyme activity and decreased the inflammation. However, noni fruit juice supplementation increased exercise-induced oxidative stress and catabolism in middle-aged men.

以文找文

期刊論文
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