Ventilators are common medical equipment in intensive care units. Ventilator-associated pneumonia increases patients' lengths of hospital stay and mortality rates in intensive care units. The 2004 US medical quality policy proposed a new protocol for bundled care to effectively reduce the occurrence of ventilator-associated pneumonia. The completion rate of the bundled care for patients with ventilator-associated pneumonia had previously been only 42% in our unit. After following the aforementioned protocol, in our unit, the completion rate increased to 96%, and the incidence rate of ventilator-associated pneumonia infection decreased from 2.55 per mille to 1.56 per mille, thereby achieving our goal. We hope that this protocol can improve the quality of care for ventilator-associated pneumonia.