Disease is a challenging experience in the lives of humans. How to "discover meaning" and even deepen physical and mental transformation throughout the course of a burdensome disease experience is the spiritual direction of all patients who pursue transcendence to against all odds. The research in this paper intends to explore the Chinese "eminent monks" way of transforming diseases. Based on observations of the disease experiences of Zi-bo Zhen-ke and Han-shan De-qing, two eminent monks in the late Ming Dynasty with their works written in the form of poetry and literature, to search what insight was gained from different levels of spiritual transformation-based implications associated with experiences of disease suffering, and how they "took the disease as the way", thereby achieving the pursuit of awakening and freedom.