This case report describes a 55-year-old male patient who suffered from right cerebral artery infarction with left hemiplegia. The main problem is that the patient faced the roles strain with his caregiver, who is the only one caregiver to take care of him. During this period from May 28 to June 26, 2015, we used ways of techniques of observation, communications, and talks directly involved in care to collect data. By Gordon eleven functional assessment, the main healthy problems are 1. Physical Activity Dysfunction, 2. Ineffective Individual Coping, 3 Caregiver Roles Strain. In nursing process, We followed the guideline established to build a trust and therapeutic relationship between patients and their caregivers. established the trust and therapeutic relationship with patients and caregivers. by using of listening skills and referral background similar rehabilitation success stories to alleviate anxiety and confusion of the disease, the plan to enhance cooperation degree, Through the patient and the rehabilitation team to develop rehabilitation plans, physical activity function were increased. For caregivers, we reduced the skills shortage of caregivers and the concern of role reversal with communicating, talking care of patient, and enhancing disease-related skills. At last, We hope that through sharing this nursing experience, and nurses can play their unique roles in the future.