Twenty one hundred and seventy eight Air.erican college students and thirteen hundred and sixty Chinese students have been invited to participate in this research project. Their answer sheets to the Strong-Camptell Interest Inventory were separately collected from the University of Wisconsin, Madison and the Fu Jen University, Taipei. The major findings are the following: (1) among the female groups, there were 108 items out of 325 which differentiated between the "Likes" of American and Chinese by 15 or more, and among the two male groups, 84 items carried 15 or more response differences; (2) the responses of American females to the SCII were statistically different from those of the Chinese female group on 255 items and between the two male groups, differences with statistical significance were found on 262 items; (3) the response differences between American and Chinese college students to the SCII items indicate that a cultural factor plays an important role in influencing vocational interests.