This research was designed to compare the effects of three different teaching methods and materials on the AIDS knowledge, attitude and behavior intention of a vocationalschool students."A nonequivalent-control and an experimental groups design" was usedin this study. Through April 18 to June 6, 1994,360 tenth grade students in Taipai a highschool were selecte d to be the subjects. The tudents of six classes in the experimentalgroup, received a 50-minute education program While the students in the control groupdid not receive any intervention. The six classes of the experimental group were dividedinto three subgroups. In subgroup(1), students viewed projectiles and took a lecture inAIDS education; in subgroup(2), students viewed projectiles and had small group discussions about AIDS education; in subgroup(3), students viewed a videotape and bed a discussion about AIDS education. All of the students completed three tests, including pretest, posttest and post -posttest. Results revealed that the contrasts between the experimental and control groups wereremarkable. The experimental group was much better in AIDS knowledge, attitude andbehavior intention. In regard to teaching method, small group discussion had a bettereffect on AIDS knowledge than lecture. However, on the aspect of behavior intention, theeffect of lecture was much better than the effect of small group discussions. In regard toteaching materials, the effect of a videotape on AIDS knowledge was better than that ofprojectiles; but attitude wise, using projectiles had a better effect than using a videotape. According to this research, AIDS knowledge, attitude andbeha vior intention of the students were significantly improved after intervention. In addition, small group discus sion combined with projectiles produced better effects on students learning in AIDS knowl edge.