This case study explores the adaptive process of a mother with a high risk newborn baby. The researcher as a participant engaged in nursing care and data collection. During nursing care process data were interpreted by the content analysis method. The results showed that the behavior reaction of the mother was divided into two stages: 1. shock and chaotic stage; 2. adjustment and reconstruction stage. During the shock and chaotic stage, the behavior modes of the mother included: (1) negative emotional response; (2) remembering the effort for ensuring the safety of the fetus ; (3) uncertainty about the status of the newborn baby. During the adjustment and reconstruction stage, the behaviors demonstrated by the mother included: (1) recomparison of the physical condition of the newborn baby; (2) recognition of the medical treatment condition of the newborn baby; (3) recognition of the physical characteristics of the newborn baby; (4) learning the work of taking care of the newborn baby. The researcher provided the proper nursing management to match the case's physical and psychosocial demands, in order to assist the case to adjust to and take responsibility for the mother role.