According to the Cancer Registry of Taiwan, the incidence rate and prevalence rate of breast cancer has been increasing rapidly. The purpose of this study was to estimate expenditures for medical care and other costs resulted from treatment of breast cancer during the first half year after the diagnosis was made. New cases of breast cancer were collected in National Taiwan University Hospital from June, 1992 to May, 1993. One hundred and forty six new cases were identified as research subjects, and 76.7% responded to the questionnaire. Major results are as follows: (1)Most of the patients were in stage II. All of the patients received surgery and most of them received 3 types of treatment. (2)The average direct (medical) cost starting from admission to six months after discharge was NT$ 126,528.9 per patient. The average middle estimate of indirect cost (production lost,traffic cost and other relaxed expenditures)was NT$ 103,292.1. The average middle estimate of total cost was NT$ 231,097.1.(3) More than half of the patients felt unco mfortable after receiving treatments for breast cancer. The later stage the patients were, the more fatigue the patients felt.(4)Elementary school education level was related to a lower, later stage and more items of treatment were related to a higher direct cost. Patients older than 65 years had a lower, those who lived in areas more distance from Taipei had a higher indirect cost .Elementary school education level was related to a lower, more distance from Taipei and later stage of the disease were relat ed to a higher total cost. Those who lived in areas more distance from Taipei and more items of treatment were related to a higher intangible cost. The authors suggest that in order to reduce costs of treatment of breast cancer to the individual, family and society, the health authority should enhance the health education about early detection and early treatment of breast cancer, and a more equal allocation of health care resources.