Case-based reasoning is a new research paradigm in artificial intelligence and computer-aided design. This paper depicts the obersvations and analysis of case-base design and reasoning from design behavioral studies of case adaptatio. Four design experiments are undertaken to examine the role of cases in design, and how designers conduct case-based design and reasoning. The research also examines how designers apply dimensional and topological adaptation, and the differences of case adaptation by novice and experienced designers. In conclusion, this study provides the comparative analysis from the above observations. Case studies can facilitate design prototyping, and case-based design is useful for design formation. However, cases have limitations in adaptation. Case selection is related to case context, the design ability and intentions of the users.