Most of the researches show that narcotic analgesics do not promote an athlete's performance. However, some athletes attempt to use narcotic analgesics to reduce stress and anxiety. They may use the drugs to hide an existing serious injury from training or competitions. However, it will cause further injury, permanent damage or physical dependence on the drugs. Narcotic analgesics may be a danger to athletes because of its side effect and addiction. It may induce toxication to death by overdose. Besides, Narcotic analgesics are strictly controlled by legislation in Taiwan. This article will introduce narcotic analgesics' categories, mechanism, pharmacokinetics, pharmacological action, and side effects. The athlete's misuse of narcotic analgesics, athletes' sport ability, prevention and proposals for coaches and athletes will also be discussed in this paper.