According to an incident report of the medical center, patient's falls are the No.1 cause of accidents in the patient population. Therefore, how to prevent patients' falls was the top pripority to ensure the patient's quality of care. This study was designed according to the characteristics of neurosurgical patients by using a "Fall risk factor assessment score" to identify patients at risk of falls; to establish protocol for preventing patients' falls; and through the process to educate nurses to detect high risk of patients fall. The audit of patients' falls began at the neurosurgical ward in March 1995. The results showed: (1) The average of the accuracy of reporting high risk patients for fall was 93 .59 % which was much improved from the data of 56.6% 1994. (2) The incident rate of patients' fall was below threshold which was 0.1 % except 3 months. (3) The effectiveness of prevention intervention was 93.07%, which was also remarkably improved over the data of 1994. In the future, we would revise the "Fall risk factor assessment score" and test the reliability to ensure the accuracy of the tool. Also, we would establish the standard of care for preventing patients' falls and continue monitoring the process to reduce the incident rate of falls.