With rapid progress of Information Technology, followed by the publication of DICOM 3 and HL7 standard, the technological development of medical information has strongholds in two aspects. One is the PACS technique, based upon the image transmission, image processing and display. The other is the word descriptions of storage and management of electronic health file. However, they are both expensive, time-consuming, and difficult to integrate with HIS. (Hospital Information System). The purpose of this study is develop the Nuclear Medicine Information System (NMIS). By jointing effort with our colleague in Information System Department, we establish the micro-PACS system based on existing reporting system incorporated with imaging file conversion. Using the window NT server together with TCP/IP protocol, we integrated the nuclear medicine image files and text report files. Also we make use of ethernet network to interconnect media data in the nuclear medicine department, so as to store all of them in CD-Rom sever. The integrated data can provide clinicians easier and more informative patient data inquiry and printing. The further improvement will be linking up to internet, and achieve the goal of remote transmission. IRIS not only benefits the medical image archiving and storage, but also facilitates physician in patient report retrieval. We anticipate with the success of the system, our department will be one step ahead toward Filmless management and Telemedicine.