:::

詳目顯示

回上一頁
題名:巴金森氏症之新知--病因、治療與護理
書刊名:護理雜誌
作者:唐福瑩王昀邱蔡賢林欣榮
作者(外文):Tang, F. I.Wang, Y.Chiu, T. H.Lin, S. Z.
出版日期:1999
卷期:46:3
頁次:頁79-85
主題關鍵詞:巴金森氏症病因治療護理Parkinson's diseaseEtiologyTreatmentNursing
原始連結:連回原系統網址new window
相關次數:
  • 被引用次數被引用次數:期刊(0) 博士論文(0) 專書(0) 專書論文(0)
  • 排除自我引用排除自我引用:0
  • 共同引用共同引用:0
  • 點閱點閱:83
     巴金森氏症是中腦多巴胺神經系統退化,所引起的慢性運動障礙疾病,此病的病 因,直到目前仍沒有定論,其中包括基因,抽煙,人格,環境,腦部損傷,以及金屬離子等 ,都是探討的方向。 而在人類的經驗中,老化以及非法製造 demerol 的過程中,產生的一 種多巴胺神經毒素 MPTP ( 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine ),而導致 中腦多巴胺神經系統退化,是目前研究中較確定的因素。巴金森氏症的治療,主要仍以補充 多巴胺的前驅物 Levodopa 為主,其他的藥物包括多巴胺作用劑( agonist ), 抗乙醯膽 鹼藥物( anticholinergic drug ), 單胺氧化�t -G 的抑制劑( MAO-B inhibitor )。 而目前的研究朝向抗氧化劑,金屬離子捕捉劑的應用,以及胚胎組織多巴胺細胞的移植,連 同最新的神經生長因子的注射,都是巴金森氏症可能的治療方式。巴金森氏症的護理在生理 方面主要是協助活動,以及避免肺炎及異物吸入的危險,在心理方面的則重於處理病人的憂 慮與癡呆的現象。
期刊論文
1.(1989)。Effect of deprenyl on the progression of disability in early Parkinson's disease. The Parkinson Study Group。New England Journal of Medicine,321(20),1364-1371。  new window
2.Aarsland, D.、Tandberg, E.、Larsen, J. P.、Cummings, J. L.(1996)。Frequency of dementia in Parkinson disease。Archives of Neurology,53(6),538-542。  new window
3.唐福瑩、王昀、邱蔡賢(19980700)。GDNF對黑質--紋狀體多巴胺系統之作用。醫學研究,19(1),12-21。  延伸查詢new window
4.唐福瑩、王昀、邱蔡賢、林欣榮(19990400)。巴金森氏症之胚胎移植治療。護理雜誌,46(2),77-84。new window  延伸查詢new window
5.唐福瑩、邱蔡賢、王昀(19980700)。Substance P對黑質--紋狀體多巴胺系統之作用。醫學研究,19(1),1-11。  延伸查詢new window
6.Fallon, J.、Matthews, R. T.、Hyman, B. T.、Beal, M. P.(1997)。MPP+ produces progressive neuronal degeneration which is mediated by oxidative stress。Experimental Neurology,144(1),193-198。  new window
7.Ekberg, O.、Feinberg, M.(1992)。Clinical and demographic data in 75 patients with near-fatal choking episodes。Dysphagia,7(4),205-208。  new window
8.Dexter, D. T.、Carayon, A.、Javoy-Agid, F.、Agid, Y.、Wells, P. R.、Daniel, S. E.、Lees, A. J.、Jermer, P.、Marsden, C. D.(1991)。Alterations in the levels of iron, ferritin and other trace metals in Parkinson's disease and other neurodegenerative diseases affecting the basal ganglia。Brain,114(4),1953-1975。  new window
9.Burns, R. S.、Chiueh, C. C.、Markey, S. P.、Ebert, M. H.、Jacobowitz, D. M.、Kopin, I. J.(1983)。A primate model of parkinsonism: Selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine。Proceedings of the National Academy of Sciences of the United States of America,80(14),4546-4550。  new window
10.Brouillet, E. P.、Shinobu, L.、McGarvey, U.、Hochberg, F.、Beal, M. E.(1993)。Manganese injection into the rat striatum produces excitotoxic lesions by impairing energy metabolism。Experimental Neurology,120(1),89-94。  new window
11.Sanchez-Ramos, J. R.、Ortoll, R.、Paulson, G. W.(1996)。Visual hallucinations associated with parkinson disease。Archives of Neurology,53(12),1265-1268。  new window
12.Menza, M. A.、Forman, N. E.、Goldstein, H. S.、Golbe, L. I.(1990)。Parkinson's disease, personality, and dopamine。Journal of Neuropsychiatry & Clinical Neurosciences,2(3),282-287。  new window
13.Koller, W.、Vetere-Overfield, B.、Gray, C.(1990)。Environmental risk factors in Parkinson's disease。Neurology,40,1218-1221。  new window
14.Greenamyre, J. T.、O'Brien, C. F.(1991)。N-methyl-D-aspartate antagonists in the treatment of Parkinson's disease。Archives of Neurology,48(9),977-981。  new window
15.Golbe, L. I.、Cody, R. A.、Duvoisin, R. C.(1986)。Smoking and Parkinson's disease. Search for a doseresponse relationship。Archives of Neurology,43(8),774-778。  new window
16.Vieregge, R.、Schiffke, K. A.、Friedrich, H. J.、Muller, B.、Ludin, H. R.(1992)。Parkinson's disease in twins。Neurology,42(8),1453-1461。  new window
17.Tang, F. I.、Tien, L. T.、Zhou, R. C.、Hoffer, B. J.、Wang, Y.(1998)。Intranigral ventral mesencephalic grafts and nigrostriatal injections of glial cell line-derived neurotrophic factor restore dopamine release in the striatum of 6-hydroxydopamine-lesioned rats。Experimental Brain Research,119(3),287-296。  new window
18.Tang, P. I.、Chiu, T. H.、Wang, Y.(1998)。Electrochemical studies of the effects of substance P on dopamine terminals in the rat striatum。Experimental Neurology,152,41-49。  new window
19.Snyder, S. H.、D'Amato, R. J.(1985)。Predicting Parkinson's disease。Nature,317(6034),198-199。  new window
其他
1.Vieregge, P.,Kortke, D.,Meyer-Bomsen, C.(1994)。Medical management and social status of elderly Parkinson patients。  new window
2.Viskum, B.,Juul, S.(1992)。Accidental falls in nursing homes: A study on the role of drugs in accidental falls in nursing homes。  new window
 
 
 
 
第一頁 上一頁 下一頁 最後一頁 top