A meta-analysis was conducted to study the relationship between socioeconomic status and mental health in Chinese children and adolescents. Through literature retrieval, 62 articles and 126 independent effect sizes were selected together with 111,117 participants, which met the inclusion criteria of meta-analysis. The results showed that socioeconomic status was positively correlated with positive indicators of mental health, and negatively correlated with negative indicators of mental health. In addition,the relationship between socioeconomic status and mental health was moderated by different levels of socioeconomic status, types of positive indicators of mental health and publication year, but not by the types of negative indicators of mental health, participants and region. These results indicate that socioeconomic status is closely related to mental health in children and adolescents, and different levels of socioeconomic status, types of positive indicators of mental health and publication year are important moderating variables.