The Yi-ology of Liu Zongzhou (1578-1645), which is derived from the philosophy of heart/mind (xin) of the Renpu, represents the philosophy of the Yi jing through the study of the heart/mind. On the one hand, Liu Zongzhou considered that the heart/mind can be equated with Yi changes, and he illustrated Yi changes with the heart/mind. Firstly, the sages brought about Yi-ology to propagate the truth with the He tu and the Luo shu diagrams as foundations. The way of heaven was based on the Yi-ology stemming from the He tu scheme. The way of earth was based on the Luo shu configuration. Secondly, the sages created the Eight Trigrams with the heart/mind according to the study of the Yi jing. They kept the Dao of Yi changes in mind, studied the laws of nature with the assistance of Yi-ology, and created the Eight Trigrams to simulate all things and situations on the earth. On the other hand, Liu Zongzhou also suggested that Yi changes could cast light on the heart/mind. Firstly, the surface representations are often in contrast to the real heart. The heart/mind will manifest these representations of itself, and is always there. That is to say, “the mutual reinforcement and neutralization of each other” is consistent with the idea that “the great ultimate (Taiji) is in itself since there is no other organizing pole.” Secondly, the transcendental and the realistic are the same in the end. In other words, yin and yang are born as two opposing principles in nature with the purpose of unifying the way of heaven and the way of earth, the innate and the acquired. Then, the four virtues and the four qi could be balanced and integrated together. The Yi-ology of Liu Zongzhou proposes the idea of the integration of body and spirit, and Yi is the instrument according to which one becomes a profound person. The personalities of people with noble characters will be manifested when Yi is applied. People with noble characters value the heart/mind with divine respect and thus they see how things will develop from their first small beginnings. They attach importance to variations in order to reform and mend their ways to become good.