Since hospice provides a holistic mode of care for ill children and youth with terminal condition, it could enhance the quality of life and maintain their autonomy with dignity. It is commonly believed that children has limited cognition and can't understand disease and death. Or tension and conflict within the family were often caused due to family members' intention of concealing the medical situation. As the active treatment becomes futile, the family members often struggle with receiving palliative treatment. This study is a report on two clinical cases, emphasizing on the spiritual care received by two terminally ill cancer children in hospice. Based on the care process, it was found that the spiritual care for the ill children involved the following four aspects: 1. informing the status of disease, 2. reconciliation of relationship, 3. reducing death anxiety, 4. Religious counseling. For the first case, the process went as follows: 1. discussing the status of disease and letting out emotion by building up the relationship. 2. a life review being conducted for reconnecting and reconciliating the relationship. 3. affirming the life meaning to facilitate the expression of love, sorry, thanks and farewell. For the second one, 1.helping express regrets and apologies to reduce guilty feeling toward the early ant-killing experience. 2. respecting the autonomy during the final stage. 3. activating the inner strength and reducing the death anxiety by reciting the Buddha's name. Attending to the ways of spiritual care for children in hospice as in this report could help facilitate ”good death” of ill children. Death is a chasm of life, but the good death of ill children could leave no regret for the dead and comfort the bereaved family members.