This paper assesses the impact of the current Indo-Pacific Strategy on Taiwan's defense of Kinmen and Matsu in light of the changes in the international situation, and makes recommendations on the direction of the development of the defense of Kinmen and Matsu. The paper first reviews and discusses the origin and development of the Indo-Pacific strategy. Since the release of the 2022 "Indo-Pacific Strategy Report," we can clearly comprehend the content of the Biden administration's Indo-Pacific strategy, structured across three dimensions: "investment," "alliance," and "competition." The aim is to maintain and strengthen its own capabilities, deepen alliances or partnerships in the Indo-Pacific region, and facilitate the containment of China. With factors such as the deterioration of U.S.-China relations and the implementation of the Indo-Pacific strategy, Taiwan’s international and strategic status has been elevated, and peace in the Taiwan Strait has gained international attention. However, despite Taiwan's strategic importance, the significance of its strategic position does not extend to Kinmen and Matsu. In light of the widening gap in military power across the Taiwan Strait, the possibility of the U.S. military opposing the intervention of Taiwan's main island to aid the outlying islands, particularly Kinmen and Matsu, in the event of an attack, becomes more pronounced. Therefore, a defense strategy independent of external support is essential. Finally, regarding the independent operations of Kinmen and Matsu, when facing traditional naval invasion defense scenarios, there is a need to enhance automated defense weapon systems, such as "short-range automated defense weapon systems" and "shore defense rocket systems." However, challenges related to automatic ammunition loading need resolution. Additionally, ongoing efforts are required to strengthen air defense capabilities, particularly against drone swarms and armed helicopters. Furthermore, to align with the defense operations on Taiwan, the article suggests that the military should persist in developing extended-range multiple rocket launchers to reduce costs and utilizing radar systems on outlying islands to support Taiwan's defense operations.