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題名：耐力運動後補充麩醯胺酸胜肽對恢復期能量代謝物質、血液中胺基酸與疲勞指標的影響
作者：傅正思 引用關係
作者(外文)：Cheng-Sze Fu
校院名稱：國立體育學院
系所名稱：教練研究所
指導教授：許美智
學位類別：博士
出版日期：2007
主題關鍵詞：脂肪分解；肌酸激酶；糖質新生；血氨；乳酸；血糖；胰島素；游離脂肪酸；生醣性胺基酸；麩醯胺酸胜；甘油；間白素-6；麩醯胺酸；lipolysis；gluconeogenesis；creatine kinase；glutamine peptide；glycerol；IL-6；glutamine；Gluconeogenic amino acids；free fatty acid；insulin；glucose；lactate；ammonia
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本研究目的在探討耐力運動後補充麩醯胺酸胜肽對恢復期能量代謝物質、血液中胺基酸與疲勞指標的影響。實驗採用隨機雙盲交叉設計，研究對象為7名健康之大學男性學生，以強度75%VO2max之跑步機耐力運動60分鐘後補充麩醯胺酸胜肽或安慰劑(0.1g/kg•bw)，於運動前、運動後第0、15、30、45、60、90及120分鐘時採集血液進行生化值之分析，以重複量數二因子變異數分析檢定麩醯胺酸胜肽組(GP)及安慰劑組(PL)補充在運動前後各血點與兩組間各血點之差異，顯著差異水準α=.05。結果顯示，甘油濃度在運動恢復期60及90分鐘時，GP組顯著低於PL組；IL-6濃度在運動恢復期45及60分鐘時，GP組顯著高於PL組；麩醯胺酸濃度在運動恢復期15、30及45分鐘時，GP組顯著高於PL組；生醣性胺基酸濃度在運動恢復期30分鐘時，GP組顯著高於PL組；游離脂肪酸、胰島素、血糖、乳酸、血氨及肌酸激酶濃度在運動恢復期時，兩組之間並無顯著差異。由以上結果推測，補充麩醯胺酸胜肽，可提供糖質新生所需的原料來源，參與克氏循環以產生能量。麩醯胺酸胜肽可節省脂肪的能量消耗，降低脂肪分解作用，幫助運動後能量之回復。
The purpose of the study was to investigate the effects of glutamine peptide supplementation on energy metabolism substances, blood amino acids and fatigue markers during recovery from endurance exercise. In this randomized, double blind, crossover study, seven healthy male college students were randomly allocated into two treatment groups, glutamine peptide(GP) and placebo(PL). Subjects were assigned to run on a treadmill at an estimated speed corresponding to the 75% VO2max for 60 min, then the GP group received a 0.1g/kg•bw glutamine peptide solution and the PL group received hydroxypropyl methylcellulose solution, which has a similar in appearance and flavor. The concentrations of blood biochemical parameters were measured pre-exercise, post-exercise 0, 15, 30, 45, 60, 90 and 120-min. The results indicated that glycerol concentration at post-exercise 60 and 90min were significantly lower in GP group than in PL group. IL-6 concentration at post-exercise 45 and 60min were significantly higher in GP group than in PL group. Glutamine concentration at post-exercise 15, 30 and 45min were significantly higher in GP group than in PL group. Gluconeogenic amino acids concentration at post-exercise 30min were significantly higher in GP group than in PL group. There were no significantly difference in free fatty acid, insulin, glucose, lactate, ammonia and creatine kinase concentration for two groups during recovery from endurance exercise. In conclusion, ingestion of GP might help to improve gluconeogenesis, block lipolysis and increase energy utilization.
蔡崇濱（2004）。運動性疲勞的研究進展。成大體育，37（1），14-30。new window
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