以紐西蘭白兔的膝關節內側副韌帶為模型，探討運動於急性內側副韌帶受傷後的影響，並藉由生物力學的測試，來評估內側副韌帶的復原情形。共使用16隻兔子，之後隨機分成控制組與運動組，隨後在動物的右腳施行內側副韌帶完全切斷手術。術後將所有兔子置於動物籠中且不限制其活動，而運動組則一週運動3次，6週後將所有兔子犧牲解剖，並做力學測試。結果顯示，在韌帶的最大拉斷力方面：控制組與運動組分別為72.08±21.70N及95.46±22.29N，且各組的恢復百分比（受傷腳/未受傷腳）分別為54.64%及74.61%(P<0.05)；在韌帶的能量吸收能力方面；控制組與運動組分別為157.02±80.38N*mm及267.96±97.36N*mm (P<0.05)；在韌帶的強硬度方面：控制組與運動組分別為18.136±6.542 N/mm及18.721±2.696 N/mm (P>0.05)。本研究建議，運動治療可促進急性內側副韌帶傷害的癒合。

We investigated the effect of exercise on the medial collateral ligament in rabbits. Sixteen male rabbits were randomly divided into two groups. Group one was control and group two was experimental. Each group contained eight samples, New Zealand rabbit. The first group didn’t received extra therapeutic exercise treatment, and the second group received extra therapeutic exercise treatment. Each animal’s right medial collateral ligament was incised. Postoperatively, all of these animal were permitted unrestricted activated and diet in cages similar. Using the contralateral nonoperated medial collateral ligament as an internal control, we found that the ultimate load and the energy absorbed in the exercise group were increased significantly compared with the non-exercise group. The mean percent of ultimate load in the non-exercise group and the exercise group were 54.64% and 74.61%, respectively (t test, p<0.05). The stiffness in the exercise group was higher than non-exercise group, but no significantly different. The results of this study suggest that the early therapeutic exercise treatment in acute medial collateral ligament can promote the ligament healing.