The major difficulty of investment is to determine the proper timing of transactions. This research applies a technical analysis method together with an adaptive neuro-fuzzy inference system to establish a model for predicting buying/holding/selling signals of stock investment. We use the predicting rate and the rate of return to evaluate the model’s performance. The data are collected form an electronic company in Taiwan during the period form 1/1/1997 to 12/31/1998. The results indicate that the adaptive neuro-fuzzy model can help to predict the proper timing for investment and get better return on investment.