The aim of the project was to reduce the slippage rate of pig-tail and percutaneous transhepatic cholangiolar drainage (PTCD) tubes. Ten events occurring in hospital wards were analyzed. The probable factors associated with drainage tubing slippage are as follows: (1) inappropriate methods of fixation, (2) inconsistent selection of covering materials, (3) not measuring the length of the outside portion of the drainage tube, (4) inadequate placement of drainage bag and no suture supporting the drainage wound opening, leading to the intertwining of lines and the patient inadvertently sitting on the bag, and (5) irregular evaluation of the drainage care technique performed by nursing staff. Through bedside observation, analysis of the current problems, and literature search, the appropriate selection of covering materials, the correct ways of fixation, daily critical evaluation of drainage tubing, revision of the standard procedures in care of the drainage tube, innovation in the design of the tubing and the placement of the drainage bag are recommended and should be promulgated to all nursing staff in order to reduce the rate of slippage and improve the quality of nursing care.