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題名:運動訓練對骨骼肌肥大及能量氧化能力之基因表現的影響
書刊名:中華體育季刊
作者:陳聰毅 引用關係
出版日期:2004
卷期:18:1=68
頁次:頁28-34
主題關鍵詞:運動訓練基因表現肌肉肥大能量氧化
原始連結:連回原系統網址new window
相關次數:
  • 被引用次數被引用次數:期刊(1) 博士論文(0) 專書(0) 專書論文(0)
  • 排除自我引用排除自我引用:1
  • 共同引用共同引用:0
  • 點閱點閱:24
運動對肌肉細胞而言,它實屬一種刺激或壓力,會在細胞内產生一連串的連鎖反應,藉由訊息傳遞的方式使細胞產生分化、發炎、凋亡及生長等不同的作用。而這些作用可藉由分子生物的分析技術來加以研究。運動訓練會影響肌肉蛋白質調控轉錄因子、活化α肌動蛋白基因等作用,使肌肉產生肥大現象。以骨骼肌的能量氧化能力而言,運動會對控制葡萄糖攝取、肝醣合成及蛋白質合成的基因產生影響,且在運動後會增加有絲活化蛋白質酶的活化,以及活化它下游的受質,增加基因表現,使能量氧化能力增加或降低。由於目前只有少數的研究有系統的針對基因表現的變化加以探討,所以對運動訓練後之基因轉錄或轉移的適應效果之研究至今尚未清楚,亦是值得加以研究的方向。
期刊論文
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11.Kraniou, Y.、Cameron-Smith, D.、Misso, M.、Collier, G.、Hargreaves, M.(2000)。Effects of exercise on GLUT-4 and glycogenin gene expression in human skeletal muscle。Journal of Applied Physiology,88(2),794-796。  new window
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13.Sherwood, D, J.、Dufresne, S. D.、Markuns, J. F.、Cheatham, B.、Moller, D. E.、Aronson, D.、Goodyear, L. J.(1999)。Differential regulation of MAP kinase, p70s6k, and Akt by contraction and insulin in rat skeletal muscle。American Journal of Physiology - Endocrinology and Metabolism,276(5),E870-E878。  new window
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