The purpose of this study was to discuss the relationship between loadings and duration in sports, and applied it to daily exercise in order to premise safety conditions. There were 6young men (age 24.2 year ± 1.7 year, height 173.8 cm ± 6.6cm, weight 66 kg ± 6.9 kg) to participate this study. All participations in advance had to measure the resting physiological value (VO(feaf)rest, HRrest), maximum physiological value (VO(feaf)max, HRmax) and the maximum running velocity at VO(feaf)max. Then, we exerted 6 fixed intensity of personal VO(feaf)max in 70%, 60%, 50%, 40%, 30%, and 20%. During this experience, we measured VO(feaf) and HR continuously in exercise. We used them to be loadings by relative loadings, and we judged duration time by HR. The data from this experience were analyzed by non-linear regression, and the results as follow: HR=18.35+61.67e□; RVO(feaf)=10.16+62.92e□. If we apply this result to 30 minutes exercise, then the RHR=68.5% and the RVO(feaf)=65.3% are the fittest loadings. Therefore, people can set the exercise time they want to fit the loadings of this study in order to premise safety when they are in exercise.